Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2017.08.003
Abstract: ABSTRACT Age‐related cataracts are closely associated with lens chronological aging, oxidation, calcium imbalance, hydration and crystallin modifications. Accumulating evidence indicates that misfolded proteins are generated in the endoplasmic reticulum (ER) by most cataractogenic stresses. To… read more here.
Keywords: age related; unfolded protein; cytoprotection; related cataracts ... See more keywords
Optical Modeling and Physical Experiments on Ocular UV Manikins Exposure
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Access"
DOI: 10.1109/access.2018.2885533
Abstract: The prevalence of age-related cataracts is higher in Asians than Caucasians. Ocular ultraviolet (UV) exposure is an important environmental risk factor leading to age-related cataracts. The purpose of this paper is to clarify the effects… read more here.
Keywords: anatomy; manikin; related cataracts; age related ... See more keywords