Single-Nephron GFR in Patients With Obesity-Related Glomerulopathy
Sign Up to like & getrecommendations! Published in 2020 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2020.05.013
Abstract: Introduction Obesity-related glomerulopathy (ORG) is a slowly progressive kidney disease occurring in association with obesity. It is characterized histopathologically by glomerulomegaly, likely caused by single-nephron hyperfiltration that has not been demonstrated in humans because of… read more here.
Keywords: single nephron; related glomerulopathy; obesity related; nephron ... See more keywords
Obesity-related glomerulopathy in the presence of APOL1 risk alleles
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DOI: 10.1136/bcr-2022-249624
Abstract: Nephropathic apolipoprotein L1 (APOL1) risk alleles (G1/G2) have been associated with focal segmental glomerulosclerosis, HIV-associated nephropathy, Systemic lupus erythematosus (SLE)-associated collapsing glomerulopathy and other glomerulonephritides. These alleles confer protection from Trypanosoma brucei infections which are… read more here.
Keywords: apol1; related glomerulopathy; obesity related; risk ... See more keywords
Obesity-Related Glomerulopathy: From Mechanism to Therapeutic Target
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s334199
Abstract: Abstract Obesity-related glomerulopathy (ORG) is a secondary glomerular disease caused by obesity, with clinical manifestations such as proteinuria and glomerulomegaly. Currently, the high incidence of obesity brings a change in the spectrum of kidney diseases… read more here.
Keywords: related glomerulopathy; obesity; glomerulopathy mechanism; mechanism therapeutic ... See more keywords