Interleukin 2 receptor subunit beta as a novel hub gene plays a potential role in the immune microenvironment of abdominal aortic aneurysms.
Sign Up to like & getrecommendations! Published in 2022 at "Gene"
DOI: 10.1016/j.gene.2022.146472
Abstract: BACKGROUND Abdominal aortic aneurysm (AAA) is potentially life threatening and characterized by immune-inflammatory cell infiltration and extracellular matrix degradation. Currently, pharmacotherapy mainly aims to control risk factors without reversion of the dilated aorta. This study… read more here.
Keywords: hub; hub gene; infiltration; gene ... See more keywords
Identification of Immune-Related Hub Genes in Parkinson’s Disease
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DOI: 10.3389/fgene.2022.914645
Abstract: Background: Parkinson’s disease (PD) is a common, age-related, and progressive neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an essential role in the pathogenic process of PD. The objective of this study was to… read more here.
Keywords: immune related; hub genes; analysis; related hub ... See more keywords
Identification of tumor mutation burden-related hub genes and the underlying mechanism in melanoma
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DOI: 10.7150/jca.53697
Abstract: Background: Tumor mutation burden (TMB) has emerged as an important predictive factor for drug resistance in cancers; however, the specific mechanism underlying TMB function in melanoma remains elusive. Methods: Data on somatic mutations, RNA sequencing… read more here.
Keywords: melanoma; hub genes; related hub; tmb ... See more keywords