Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02955-y
Abstract: Immune checkpoint inhibitors (ICIs) as a cancer immunotherapy have emerged as a treatment for multiple advanced cancer types. Because of enhanced immune responses, immune-related adverse events (irAEs), including endocrinopathies such as hypophysitis, have been associated… read more here.
Keywords: immune checkpoint; related hypophysitis; hypophysitis; ici related ... See more keywords
Elevated CK from immune checkpoint inhibitor- related hypophysitis: a case report
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Chemotherapy"
DOI: 10.1080/1120009x.2024.2359838
Abstract: Abstract Immune checkpoint inhibitors (ICIs), have emerged to the forefront of management for various advanced cancers, such as melanoma, lung cancer and renal cell carcinoma. Immune checkpoints such as CTLA-4 and PD-1 serve to inhibit… read more here.
Keywords: immune checkpoint; related hypophysitis; checkpoint inhibitor; case ... See more keywords
Sellar germinoma mimicking IgG4-related hypophysitis: a case report
Sign Up to like & getrecommendations! Published in 2022 at "BMC Endocrine Disorders"
DOI: 10.1186/s12902-021-00930-3
Abstract: Background The differential diagnosis of IgG4-related hypophysitis and other inflammatory diseases or tumors involving sellar region is challenging even after sellar biopsy. Sellar germinoma is usually infiltrated by lymphocytes or plasma cells, and may be… read more here.
Keywords: sellar germinoma; hypophysitis case; related hypophysitis; igg4 related ... See more keywords
Atypical IgG4 related hypophysitis revealed by submandibular sialadenitis: a case report
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DOI: 10.2478/enr-2025-0014
Abstract: Abstract Objective. IgG4-related disease is a fibro-inflammatory multisystemic condition with lesions mimicking tumors. Involvement of the hypophysis is rare and the first case of IgG4-related hypophysitis was described in 2004. Typically, it is revealed by… read more here.
Keywords: igg4 related; revealed submandibular; case; related hypophysitis ... See more keywords
Treatment and outcome of a boy with lgG4-related hypophysitis caused by SARS-CoV-2 re-infection
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DOI: 10.3389/fendo.2025.1663029
Abstract: Rationale SARS-CoV-2 infection can directly and indirectly affect the nervous system, including the hypothalamus and pituitary, and potentially cause IgG4-related hypophysitis. Patient concerns A 4-year-old Chinese boy presented with arginine vasopressin deficiency (AVP-D, previously called… read more here.
Keywords: sars cov; boy; cov infection; related hypophysitis ... See more keywords