Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.887497
Abstract: Intestinal fibrosis is considered to be a chronic complication of inflammatory bowel disease (IBD) and seriously threatening human health. Effective medical therapies or preventive measures are desirable but currently unavailable. Metformin has been proved to… read more here.
Keywords: colitis related; intestinal fibrosis; fibrosis; metformin ... See more keywords
Ferroptosis as a therapeutic target for inflammation-related intestinal diseases
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DOI: 10.3389/fphar.2023.1095366
Abstract: Ferroptosis is an iron-dependent programmed cell death characterized by reactive oxygen species-induced lipid peroxidation and resultant membrane damage. Recent research has elucidated the mechanism of ferroptosis and investigated the relationship between ferroptosis and various diseases,… read more here.
Keywords: inflammation; ferroptosis therapeutic; intestinal diseases; inflammation related ... See more keywords
Beneficial Effect of Kidney Bean Resistant Starch on Hyperlipidemia—Induced Acute Pancreatitis and Related Intestinal Barrier Damage in Rats
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DOI: 10.3390/molecules27092783
Abstract: Accumulating attention has been focused on resistant starch (RS) due to its blood-lipid-lowering activities. However, reports on the potential bioactivities of RS for preventing hyperlipidemia acute pancreatitis (HLAP) are limited. Therefore, in this study, an… read more here.
Keywords: effect kidney; hyperlipidemia; acute pancreatitis; related intestinal ... See more keywords
Biological characteristics of IL-6 and related intestinal diseases
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DOI: 10.7150/ijbs.51362
Abstract: The intestine serves as an important digestive and the largest immune organ in the body. Interleukin-6(IL-6), an important mediator of various pathways, participates in the interactions between different kinds of cells and closely correlates with… read more here.
Keywords: characteristics related; intestinal diseases; biological characteristics; related intestinal ... See more keywords