Multi-omics characterization and validation of MSI-related molecular features across multiple malignancies.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119081
Abstract: HEADINGS AIMS To establish a microsatellite instability (MSI) predictive model in pan-cancer and compare the multi-omics characterization of MSI-related molecular features. MATERIALS AND METHODS We established a 15-gene signature for predicting MSI status and performed… read more here.
Keywords: msi; related molecular; molecular features; msi related ... See more keywords
Molecular characterization of dromedary camel potential fertility: A new approach
Sign Up to like & getrecommendations! Published in 2019 at "Small Ruminant Research"
DOI: 10.1016/j.smallrumres.2018.11.004
Abstract: Abstract Male fertility is one aspect of animal reproduction that was targeted by many biotechnology studies aiming to improve reproductive efficiency and, hence, productive capacity in different species. The current investigation aimed to determine expression… read more here.
Keywords: fertility related; fertility; molecular markers; potential fertility ... See more keywords
A novel cuproptosis-related molecular pattern and its tumor microenvironment characterization in colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.940774
Abstract: Cuproptosis, or copper-induced cell death, has been reported as a novel noncanonical form of cell death in recent times. However, the potential roles of cuproptosis in the alteration of tumor clinicopathological features and the formation… read more here.
Keywords: cuproptosis; related molecular; colorectal cancer; tumor ... See more keywords
Aging-Related Molecular Pathways in Chronic Cholestatic Conditions
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2019.00332
Abstract: Aging is commonly defined as the time-dependent functional decline of organs and tissues. Average life expectancy has increased considerably over the past century and is estimated to increase even further, consequently also the interest in… read more here.
Keywords: chronic cholestatic; pathways chronic; cholestatic conditions; related molecular ... See more keywords
Cuproptosis-related molecular subtypes direct T cell exhaustion phenotypes and therapeutic strategies for patients with lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1146468
Abstract: Background: T cell exhaustion (TEX) heterogeneity leads to unfavorable immunotherapeutic responses in patients with cancer. Classification of TEX molecular phenotypes is pivotal to overcoming TEX and improving immunotherapies in the clinical setting. Cuproptosis is a… read more here.
Keywords: molecular subtypes; tex; related molecular; cell exhaustion ... See more keywords
Identification of senescence-related molecular subtypes and key genes for prostate cancer
Sign Up to like & getrecommendations! Published in 2022 at "Asian Journal of Andrology"
DOI: 10.4103/aja202258
Abstract: We identified distinct senescence-related molecular subtypes and critical genes among prostate cancer (PCa) patients undergoing radical prostatectomy (RP) or radical radiotherapy (RT). We conducted all analyses using R software and its suitable packages. Twelve genes,… read more here.
Keywords: molecular subtypes; prostate cancer; related molecular; senescence related ... See more keywords