Incidence and risk factors for medication‐related osteonecrosis after tooth extraction in cancer patients—A systematic review
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DOI: 10.1002/cre2.698
Abstract: Antiresorptive medication has been reported to be associated with medication‐related osteonecrosis of the jaw (MRONJ). This systematic review aims at investigating the incidence of and risk factors for MRONJ after tooth extractions in cancer patients… read more here.
Keywords: medication; medication related; incidence risk; systematic review ... See more keywords
Medication‐related osteonecrosis of the jaw: A literature review and update
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DOI: 10.1002/dvg.23500
Abstract: Since the initial description of medication‐related osteonecrosis of the jaw (MRONJ) almost two decades ago, the potential pathophysiology and risk factors have been elaborated on in many investigations and guidelines. However, the definitive pathophysiology based… read more here.
Keywords: medication; medication related; review; related osteonecrosis ... See more keywords
SIRT1 Gene SNP rs932658 Is Associated With Medication‐Related Osteonecrosis of the Jaw
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DOI: 10.1002/jbmr.4185
Abstract: Medication‐related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse drug reaction. Our previous whole‐exome sequencing study found SIRT1 intronic region single‐nucleotide polymorphism (SNP) rs7896005 to be associated with MRONJ in cancer patients… read more here.
Keywords: related osteonecrosis; snp rs932658; medication related; rs932658 ... See more keywords
Therapeutic effect of fluvastatin on medication-related osteonecrosis of the jaw.
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DOI: 10.1002/jper.21-0294
Abstract: BACKGROUND Refractory jaw osteonecrosis that occurs in osteoporotic or cancer patients treated with bisphosphonates is called medication-related osteonecrosis of the jaw but its underlying mechanism is unclear. Statins, therapeutic agents for dyslipidemia, lower blood low-density… read more here.
Keywords: medication related; jaw; related osteonecrosis; osteonecrosis jaw ... See more keywords
Investigation of Sustained BMP Delivery in the Prevention of Medication-Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model.
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DOI: 10.1002/mabi.201900226
Abstract: Medication-related osteonecrosis of the jaw (MRONJ) poses an ongoing challenge for clinicians and researchers. Currently, there is a lack of preventative measures available for at-risk patients undergoing tooth extractions, especially those with prior bisphosphonate treatment… read more here.
Keywords: mronj; related osteonecrosis; jaw mronj; delivery ... See more keywords
A comparative effectiveness pilot study of teriparatide for medication-related osteonecrosis of the jaw: daily versus weekly administration
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DOI: 10.1007/s00198-019-05199-w
Abstract: Summary We studied the effectiveness of teriparatide (TPTD) for treating medication-related osteonecrosis of the jaw (MRONJ) in patients with osteoporosis and examined differences in the clinical outcomes following daily versus weekly TPTD. The outcomes were… read more here.
Keywords: tptd; related osteonecrosis; group; versus weekly ... See more keywords
Prognosis by cancer type and incidence of zoledronic acid–related osteonecrosis of the jaw: a single-center retrospective study
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DOI: 10.1007/s00520-022-06839-4
Abstract: Survival time after bisphosphonate use has been increasingly recognized to be associated with the incidence of medication-related osteonecrosis of the jaw (MRONJ); however, this has not been elucidated sufficiently in the literature. This study aimed… read more here.
Keywords: cancer; osteonecrosis jaw; prognosis; related osteonecrosis ... See more keywords
Drug holiday clinical relevance verification for antiresorptive agents in medication-related osteonecrosis cases of the jaw
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DOI: 10.1007/s00774-019-01035-7
Abstract: Treatment strategies of medication-related osteonecrosis of the jaw (MRONJ) are controversial. Recently, surgical treatment has been reported as superior to nonsurgical treatment, but the contribution discontinued antiresorptive agent use during MRONJ treatment remains unclear. This… read more here.
Keywords: related osteonecrosis; antiresorptive agents; treatment; drug ... See more keywords
Imaging findings and treatment outcomes of a rare subtype of medication-related osteonecrosis of the jaw
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DOI: 10.1007/s00774-021-01267-6
Abstract: In our previous study, we found a rare type of medication-related osteonecrosis of the jaw (MRONJ), which shows periosteal reaction (PR) at a site distant from osteolytic lesions or the extraction site (periosteal reaction dominant… read more here.
Keywords: related osteonecrosis; prd type; treatment; medication related ... See more keywords
Surgical treatment of 61 consecutive patients with maxillary stage 3 medication–related osteonecrosis of the jaws using a pedicled buccal fat pad
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DOI: 10.1007/s10006-022-01061-2
Abstract: Buccal fat pad (BFP) is used for the closure of large oroantral defects caused by surgical removal of the necrotic bone in patients with medication-related osteonecrosis of the jaw (MRONJ). This study aimed to evaluate… read more here.
Keywords: related osteonecrosis; buccal fat; fat pad; medication related ... See more keywords
Usefulness of quantitative bone SPECT/CT for medication-related osteonecrosis of the jaw in clinical settings
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DOI: 10.1007/s11604-021-01226-1
Abstract: This study was conducted to investigate the clinical utility of quantitative bone single-photon computed tomography-computed tomography (SPECT/CT) for detection and classification for medication-related osteonecrosis of the jaw (MRONJ). Fifty-nine patients (69 lesions) clinically diagnosed as… read more here.
Keywords: bone; quantitative bone; suvmax suvpeak; bone spect ... See more keywords