Plasma calcitonin gene‐related peptide (CGRP) in migraine and endometriosis during the menstrual cycle
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51360
Abstract: Migraine, endometriosis, and the comorbidity of both are frequent pain disorders of special relevance for women. The neuropeptide calcitonin gene‐related peptide (CGRP) is critically involved in migraine, and circumstantial evidence suggests a role in endometriosis.… read more here.
Keywords: endometriosis; related peptide; gene related; calcitonin gene ... See more keywords
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300516
Abstract: The local application of drug-loaded bioactive scaffold materials is one of the important directions to solve the clinical problem of osteoporotic (OP) bone defects. This study retains the advantages of drug loading and mechanical properties… read more here.
Keywords: bone; related peptide; osteoporotic bone; parathyroid hormone ... See more keywords
Anti‐migraine Calcitonin Gene–Related Peptide Receptor Antagonists Worsen Cerebral Ischemic Outcome in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Neurology"
DOI: 10.1002/ana.25831
Abstract: Calcitonin gene–related peptide (CGRP) pathway inhibitors are emerging treatments for migraine. CGRP‐mediated vasodilation is, however, a critical rescue mechanism in ischemia. We, therefore, investigated whether gepants, small molecule CGRP receptor antagonists, worsen cerebral ischemia. read more here.
Keywords: antagonists worsen; related peptide; gene related; calcitonin gene ... See more keywords
Efficacy and safety of calcitonin gene‐related peptide antagonists in migraine treatment: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2542
Abstract: We systematically reviewed the efficacy and safety of Calcitonin Gene‐Related Peptide (CGRP) antagonists for migraine treatment. read more here.
Keywords: calcitonin gene; safety calcitonin; related peptide; antagonists migraine ... See more keywords
Calcitonin gene‐related peptide: An intra‐articular therapeutic target for TMJ disorders
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.606
Abstract: The goal of this project was to evaluate the role of calcitonin gene‐related peptide (CGRP) in the development of arthritis. read more here.
Keywords: calcitonin gene; related peptide; intra articular; peptide intra ... See more keywords
Calcitonin Gene-Related Peptide Antagonists and Therapeutic Antibodies.
Sign Up to like & getrecommendations! Published in 2019 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2018_173
Abstract: The calcitonin gene-related peptide (CGRP) receptor is composed of the calcitonin receptor-like receptor (CLR, a class B GPCR) and a single-pass membrane protein known as receptor activity modifying protein type 1 (RAMP1). The levels of… read more here.
Keywords: cgrp; related peptide; gene related; calcitonin gene ... See more keywords
Identification and accurate quantification of structurally related peptide impurities in synthetic human C-peptide by liquid chromatography–high resolution mass spectrometry
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1155-y
Abstract: AbstractPeptides are an increasingly important group of biomarkers and pharmaceuticals. The accurate purity characterization of peptide calibrators is critical for the development of reference measurement systems for laboratory medicine and quality control of pharmaceuticals. The… read more here.
Keywords: peptide; peptide impurities; mass; related peptide ... See more keywords
Elevated circulating levels of xenopsin-related peptide-1 are associated with polycystic ovary syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-017-4493-7
Abstract: PurposeThis study was conducted to compare serum xenopsin-related peptide-1 (XP-1) levels in women with polycystic ovary syndrome (PCOS) and in healthy women and to determine the role of XP-1 levels in PCOS.MethodsForty patients with PCOS… read more here.
Keywords: polycystic ovary; ovary syndrome; xenopsin related; related peptide ... See more keywords
Is calcitonin gene-related peptide a modulator of menopausal vasomotor symptoms?
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1777-z
Abstract: PurposeCalcitonin gene-related peptide (CGRP) is a neuropeptide widely distributed in the central and peripheral nervous systems, which is known as a potent vasodilator. Postmenopausal women who experience hot flushes have high levels of plasma CGRP,… read more here.
Keywords: menopausal vasomotor; cgrp; related peptide; gene related ... See more keywords
The Impact of Morphine on Reproductive Activity in Male Rats Is Regulated by Rf-Amid-Related Peptide-3 and Substance P Adjusting Hypothalamic Kisspeptin Expression
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-019-01375-z
Abstract: Obviously, opiates (e.g., morphine) are associated with the suppression and dysfunction of reproductive axis. It has been reported that substance P (SP) and RF-amid-related peptide-3 (RFRP-3) can exhibit anti-opioid effects in some regions of the… read more here.
Keywords: activity male; amid related; related peptide; expression ... See more keywords
Calcitonin gene-related peptide (CGRP)-targeted therapies as preventive and acute treatments for migraine-The monoclonal antibodies and gepants.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in brain research"
DOI: 10.1016/bs.pbr.2020.06.019
Abstract: Calcitonin Gene-Related Peptide (CGRP) plays a pivotal role in migraine pathophysiology. Two types of CGRP function-blocking modalities, monoclonal antibodies, and small molecules (gepants), have been developed to target the CGRP ligands and CGRP receptors. Four… read more here.
Keywords: monoclonal antibodies; cgrp; related peptide; gene related ... See more keywords