Imaging of Drug-Related Pneumonitis in Oncology
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DOI: 10.1055/s-0042-1755569
Abstract: Abstract Clinical applications of novel anticancer agents in the past few decades brought marked advances in cancer treatment, enabling remarkable efficacy and effectiveness; however, these novel agents are also associated with toxicities. Among various toxicities,… read more here.
Keywords: oncology; related pneumonitis; drug related; pneumonitis ... See more keywords
Programmed cell death 1 (PD‐1)/PD‐ligand 1(PD‐L1) inhibitors‐related pneumonitis in patients with advanced non–small cell lung cancer
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DOI: 10.1111/ajco.13380
Abstract: Immune‐related pneumonitis is an uncommon but potentially fatal immune‐related adverse event in advanced non–small cell lung cancer (NSCLC) patients during treatment with anti‐programmed cell death 1 (PD‐1) and programmed cell death‐ligand 1 (PD‐L1). Underlying emphysema,… read more here.
Keywords: immune related; related pneumonitis; lung cancer; cell ... See more keywords
Immune check‐point inhibitor‐related pneumonitis: acute lung injury with rapid progression and organising pneumonia with less severe clinical disease
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DOI: 10.1111/his.14704
Abstract: To improve understanding of the pathology of immune check‐point inhibitor (ICI)‐related pneumonitis, clinical, radiographic and histopathological features and outcomes were investigated in a cohort of patients who were treatment‐naive before receiving ICI inhibition, who underwent… read more here.
Keywords: related pneumonitis; lung injury; check point; point inhibitor ... See more keywords
Relationship between pneumonitis induced by immune checkpoint inhibitors and the underlying parenchymal status: a retrospective study
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DOI: 10.1183/23120541.00165-2019
Abstract: In patients with primary or secondary lung tumour treated with immune checkpoint inhibitors, immune-related pneumonitis is a rare adverse event but may evolve to respiratory failure. Prompt management is required and usually consists of treatment… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; immune related; related pneumonitis ... See more keywords
Clinical features, diagnostic challenges, and management strategies in checkpoint inhibitor-related pneumonitis
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DOI: 10.2147/cmar.s136818
Abstract: Immune checkpoint inhibitors, including cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death-1 (PD-1) inhibitors, represent an effective treatment modality for multiple malignancies. Despite the exciting clinical benefits, checkpoint inhibition is associated with a series… read more here.
Keywords: management strategies; treatment; management; related pneumonitis ... See more keywords
Proposed clinical phases for the improvement of personalized treatment of checkpoint inhibitor–related pneumonitis
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DOI: 10.3389/fimmu.2022.935779
Abstract: Background Checkpoint inhibitor–related pneumonitis (CIP) is a lethal immune-related adverse event. However, the development process of CIP, which may provide insight into more effective management, has not been extensively examined. Methods We conducted a multicenter… read more here.
Keywords: checkpoint inhibitor; acute phase; related pneumonitis; phase ... See more keywords
Advances in CT features and radiomics of checkpoint inhibitor-related pneumonitis: A short review
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DOI: 10.3389/fimmu.2023.1082980
Abstract: Checkpoint inhibitor-related pneumonitis (CIP) is a complication of immunotherapy for malignant tumors that severely limits the treatment cycles as well as endangers patients’ health. The chest CT imaging features or typing of CIP and the… read more here.
Keywords: advances features; inhibitor related; checkpoint inhibitor; related pneumonitis ... See more keywords
Case Report: Pseudoprogression With Nivolumab and Bevacizumab Followed by Recurrent Immune-Related Pneumonitis in Urothelial Carcinoma With Lung Metastasis
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DOI: 10.3389/fonc.2020.611810
Abstract: Background Combination therapy with immune checkpoint inhibitors (ICIs) and antiangiogenic agents is generally effective and well tolerated and might be effective for metastatic urothelial carcinoma (UC). However, ICI treatment is often associated with unique responses,… read more here.
Keywords: treatment; case; urothelial carcinoma; related pneumonitis ... See more keywords