Identification of immune-related subtypes of colorectal cancer to improve antitumor immunotherapy
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DOI: 10.1038/s41598-021-98966-x
Abstract: Immunotherapy involving immune checkpoint inhibitors (ICIs) for enhancing immune system activation is promising for tumor management. However, the patients’ responses to ICIs are different. Here, we applied a non-negative matrix factorization algorithm to establish a… read more here.
Keywords: immunotherapy; immune related; colorectal cancer; related subtypes ... See more keywords
Identification of Two CDK5R1-Related Subtypes and Characterization of Immune Infiltrates in Alzheimer's Disease Based on an Integrated Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/6766460
Abstract: Background Alzheimer's disease (AD) is a neurodegenerative disorder and the major cause of senile dementia. The Reelin pathway has been involved in both learning and AD pathogenesis. However, the specific Reelin-related gene signature during the… read more here.
Keywords: two cdk5r1; alzheimer disease; related subtypes; analysis ... See more keywords
Identification of pyroptosis-related subtypes and establishment of prognostic model and immune characteristics in asthma
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DOI: 10.3389/fimmu.2022.937832
Abstract: Background Although studies have shown that cell pyroptosis is involved in the progression of asthma, a systematic analysis of the clinical significance of pyroptosis-related genes (PRGs) cooperating with immune cells in asthma patients is still… read more here.
Keywords: pyroptosis; related subtypes; differentially expressed; pyroptosis related ... See more keywords
A novel cuproptosis-related subtypes and gene signature associates with immunophenotype and predicts prognosis accurately in neuroblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.999849
Abstract: Background Neuroblastoma (NB) is the most frequent solid tumor in pediatrics, which accounts for roughly 15% of cancer-related mortality in children. NB exhibited genetic, morphologic, and clinical heterogeneity, which limited the efficacy of available therapeutic… read more here.
Keywords: cuproptosis; signature; related subtypes; expression ... See more keywords