Cardiovascular Concentration-Effect Relationships of Amodiaquine and its Metabolite Desethylamodiaquine: Clinical and Pre-clinical Studies
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DOI: 10.1111/bcp.15569
Abstract: Amodiaquine is a 4‐aminoquinoline used extensively for the treatment and prevention of malaria. Orally administered amodiaquine is largely converted to the active metabolite desethylamodiaquine. Amodiaquine can cause bradycardia, hypotension, and electrocardiograph QT interval prolongation, but… read more here.
Keywords: amodiaquine metabolite; effect relationships; metabolite desethylamodiaquine; relationships amodiaquine ... See more keywords