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Published in 2020 at "ChemMedChem"
DOI: 10.1002/cmdc.202000198
Abstract: Phosphoantigens (pAgs) are small phosphorus‐containing molecules that stimulate Vγ9Vδ2 T cells with sub‐nanomolar cellular potency. Recent work has revealed that these compounds work through binding to the transmembrane immunoglobulin butyrophilin 3A1 (BTN3A1) within its intracellular…
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Keywords:
activity relationships;
relationships butyrophilin;
structure activity;
butyrophilin ligands ... See more keywords