Assessing the relative potency of (S)- and (R)-warfarin with a new PK-PD model, in relation to VKORC1 genotypes
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-017-2248-9
Abstract: PurposeThe purpose of this study is to develop a new pharmacokinetic-pharmacodynamic (PK-PD) model to characterise the contribution of (S)- and (R)-warfarin to the anticoagulant effect on patients in treatment with rac-warfarin.MethodsFifty-seven patients starting warfarin (W)… read more here.
Keywords: potency; assessing relative; effect; model ... See more keywords
Relative potency factor approach enables the use of in vitro information for estimation of human effect factors for nanoparticle toxicity in life-cycle impact assessment
Sign Up to like & getrecommendations! Published in 2020 at "Nanotoxicology"
DOI: 10.1080/17435390.2019.1710872
Abstract: Abstract The major theme of the NRC report “Toxicity Testing in the Twenty-first Century” is to replace animal testing by using alternative in vitro methods. Therefore, it can be expected that in the future in… read more here.
Keywords: toxicity; relative potency; potency factor; approach ... See more keywords
Determination of the Relative Potency of Norepinephrine and Phenylephrine Given as Infusions for Preventing Hypotension During Combined Spinal-Epidural Anesthesia for Cesarean Delivery: A Randomized Up-And-Down Sequential Allocation Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.942005
Abstract: Purpose: The relative potency of norepinephrine and phenylephrine given as boluses to treat hypotension during spinal anesthesia for cesarean delivery has been reported but few data are available for infusions. This study aimed to determine… read more here.
Keywords: hypotension; norepinephrine phenylephrine; relative potency; infusion ... See more keywords
Relative potency of different generic brands of meropenem, colistin and fosfomycin: Implications for antimicrobial therapy and antimicrobial formulary
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Medical Microbiology"
DOI: 10.4103/ijmm.ijmm_18_248
Abstract: There is a need of a relatively simple and inexpensive method for the determination of relative potency of various generic brands of antibiotics in comparison to original products. The current study describes an agar diffusion… read more here.
Keywords: microbiology; potency different; relative potency; generic brands ... See more keywords