Relative telomere length impact on mortality of COVID‐19: Sex differences
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28368
Abstract: Increasing age is associated with severity and higher mortality of COVID‐19. Telomere shortening is associated with higher risk of infections and may be used to identify those patients who are more likely to die. We… read more here.
Keywords: telomere length; rtl; mortality; mortality covid ... See more keywords
Correlation between metabolic syndrome and relative telomere length shortening in HIV/AIDS patients on combined antiretroviral therapy
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2021.111269
Abstract: BACKGROUND Components of the metabolic syndrome (MetS) play an important role in the accelerated aging process. Relative telomere length (RTL) is a marker of biological aging. The aim of our study was to determine RTL… read more here.
Keywords: relative telomere; rtl; telomere length; shortening hiv ... See more keywords
Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease.
Sign Up to like & getrecommendations! Published in 2020 at "Kidney international"
DOI: 10.1016/j.kint.2020.02.034
Abstract: Telomere length is known to be inversely associated with aging and has been proposed as a marker for aging-related diseases. Telomere attrition can be accelerated by oxidative stress and inflammation, both commonly present in patients… read more here.
Keywords: relative telomere; chronic kidney; telomere length; disease ... See more keywords
The association between early‐life relative telomere length and childhood neurodevelopment
Sign Up to like & getrecommendations! Published in 2018 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2018.01.005
Abstract: HighlightsThere was no clear association between relative telomere length, and neurodevelopmental outcomes in this study population.The majority of the outcomes show a slight, positive association with relative telomere length, although results are imprecise.Cord blood rTL… read more here.
Keywords: relative telomere; rtl; telomere length; neurodevelopmental outcomes ... See more keywords
Relative telomere length and prostate cancer mortality
Sign Up to like & getrecommendations! Published in 2018 at "Prostate Cancer and Prostatic Diseases"
DOI: 10.1038/s41391-018-0068-3
Abstract: PurposeTelomeres are essential for the maintenance of chromosomal integrity and telomere length has been associated with cancer risk and development. Aim of the present study was to analyze the prognostic value of leukocyte relative telomere… read more here.
Keywords: relative telomere; telomere length; prostate cancer; mortality ... See more keywords
Morphine may have a role in telomere shortening
Sign Up to like & getrecommendations! Published in 2021 at "Psychiatric Genetics"
DOI: 10.1097/ypg.0000000000000311
Abstract: Morphine/heroin may increase oxidative stress in drug-dependent persons. The imbalance between oxidative stress and antioxidant defense mechanisms can accelerate the shortening of telomere length. This article reports two sets of data; comparison of relative telomere… read more here.
Keywords: telomere length; relative telomere; heroin dependent; cells treated ... See more keywords
Unraveling the role of relative telomere length and CAG expansion on initial symptoms of juvenile Huntington disease
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15644
Abstract: Juvenile‐onset Huntington disease (JHD) is defined when symptoms initiate before 20 years of age. Mechanisms explaining differences between juvenile and adult onset are not fully understood. Our aim was to analyze the distribution of initial symptoms… read more here.
Keywords: telomere length; huntington disease; initial symptoms; cag expansion ... See more keywords
Cross-sectional associations between genetic polymorphisms in metabolic enzymes and longer leukocyte telomere length induced by omethoate
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20971
Abstract: Purpose This study aimed to explore the effects of genetic polymorphisms in metabolic enzymes on relative telomere length changes and explore the mechanism of canceration induced by omethoate. Materials and Methods 180 long-term omethoate-exposed workers… read more here.
Keywords: induced omethoate; relative telomere; genetic polymorphisms; telomere length ... See more keywords