The contribution of beta-2 adrenergic, muscarinic and histamine (H1) receptors, calcium and potassium channels and cyclooxygenase pathway in the relaxant effect of Allium cepa L. on the tracheal smooth muscle.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112012
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE There are report regarding therapeutic effects for Allium cepa L. (A. cepa) in Iranian traditional medicine and the plant has showed anti-inflammatory, anti-allergic, anti-hyperglycemic, antioxidant, anti-cancer, anti-hypertension, anti-hypercholesterolemia and anti-asthmatic activities in previous… read more here.
Keywords: cepa extract; cepa; effect; relaxant effects ... See more keywords
Isoindolines and phthalides from the rhizomes of Ligusticum chuanxiong and their relaxant effects on the uterine smooth muscle.
Sign Up to like & getrecommendations! Published in 2022 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2022.113159
Abstract: Three undescribed isoindoline alkaloids, (+)-(R)-3-butyl-3-ethoxyisoindolin-1-one, (+)-(3S,6S,7R)-3-butyl-6,7-dihydroxy-3-methoxy-4,5,6,7-tetrahydroisoindolin-1-one, and (-)-(3R,6S,7R)-3-butyl-6,7-dihydroxy-3-methoxy-4,5,6,7-tetrahydroisoindolin-1-one, along with nine known phthalides were isolated from a water decoction of the rhizomes of Ligusticum chuanxiong using chromatographic methods. Their structures and absolute configurations were determined… read more here.
Keywords: ligusticum chuanxiong; uterine smooth; smooth muscle; rhizomes ligusticum ... See more keywords
Mirabegron induces relaxant effects via cAMP signaling‐dependent and ‐independent pathways in detrusor smooth muscle
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DOI: 10.1111/luts.12247
Abstract: We previously found that mirabegron exerts a relaxant effect in the presence of the β3‐adrenoceptor antagonist SR58894A during carbachol‐induced contraction in human and pig detrusor. The aim of this study was to explore the possible… read more here.
Keywords: detrusor smooth; smooth muscle; relaxant effects; mirabegron induces ... See more keywords
Investigation the relaxant effects of proton pump ınhibitors and their relaxation mechanism on sheep sphincter of Oddi
Sign Up to like & getrecommendations! Published in 2019 at "Nigerian Journal of Clinical Practice"
DOI: 10.4103/njcp.njcp_115_18
Abstract: Background: Using a relaxant agent before an endoscopic retrograde cholangiopancreatography (ERCP) might reduce complications. Study Aims: We aimed to investigate the relaxant effects of proton pump inhibitors (PPIs) on sheep sphincter of Oddi (SO) and… read more here.
Keywords: sheep sphincter; sphincter oddi; relaxant effects; proton pump ... See more keywords