Down syndrome among primiparae at older maternal age: A test of the relaxed filter hypothesis.
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DOI: 10.1002/bdr2.1553
Abstract: BACKGROUND Down syndrome (DS) ranks as one of the most common birth defects in the United States. The relaxed filter hypothesis (RFH) asserts that mothers with no previous children but nearing reproductive senescence reduce fetal… read more here.
Keywords: age; older maternal; filter hypothesis; relaxed filter ... See more keywords