Relaxed 3D genome conformation facilitates the pluripotent to totipotent-like state transition in embryonic stem cells
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DOI: 10.1093/nar/gkab1069
Abstract: Abstract The 3D genome organization is crucial for gene regulation. Although recent studies have revealed a uniquely relaxed genome conformation in totipotent early blastomeres of both fertilized and cloned embryos, how weakened higher-order chromatin structure… read more here.
Keywords: totipotent like; pluripotent totipotent; like state; genome conformation ... See more keywords