ML290 is a biased allosteric agonist at the relaxin receptor RXFP1
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DOI: 10.1038/s41598-017-02916-5
Abstract: Activation of the relaxin receptor RXFP1 has been associated with improved survival in acute heart failure. ML290 is a small molecule RXFP1 agonist with simple structure, long half-life and high stability. Here we demonstrate that… read more here.
Keywords: rxfp1; accumulation; relaxin receptor; receptor rxfp1 ... See more keywords
The Relaxin-3 Receptor, RXFP3, Is a Modulator of Aging-Related Disease
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DOI: 10.3390/ijms23084387
Abstract: During the aging process our body becomes less well equipped to deal with cellular stress, resulting in an increase in unrepaired damage. This causes varying degrees of impaired functionality and an increased risk of mortality.… read more here.
Keywords: relaxin receptor; receptor rxfp3; damage; rxfp3 ... See more keywords