Structure-Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201804567
Abstract: Magnetic nanoparticles (MNPs) have been extensively explored as magnetic resonance imaging (MRI) contrast agents. With the increasing complexity in the structure of modern MNPs, the classical Solomon-Bloembergen-Morgan and the outer-sphere quantum mechanical theories established on… read more here.
Keywords: structure relaxivity; resonance imaging; magnetic resonance; magnetic nanoparticles ... See more keywords
Evolving Characteristics of Gadolinium‐Based Contrast Agents for MR Imaging: A Systematic Review of the Importance of Relaxivity
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.29367
Abstract: Gadolinium‐based contrast agents (GBCAs) are widely and routinely used to enhance the diagnostic performance of magnetic resonance imaging and magnetic resonance angiography examinations. T1 relaxivity (r1) is the measure of their ability to increase signal… read more here.
Keywords: gadolinium; relaxivity; systematic review; contrast agents ... See more keywords
A superparamagnetic polymersome with extremely high T2 relaxivity for MRI and cancer-targeted drug delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2016.10.027
Abstract: Improving the relaxivity of magnetic resonance imaging (MRI) contrast agents is an important challenge for cancer theranostics. Herein we report the design, synthesis, characterization, theoretical analysis and in vivo tests of a superparamagnetic polymersome as a… read more here.
Keywords: high relaxivity; superparamagnetic polymersome; mri; extremely high ... See more keywords
Aqueous solutions of triblock copolymers used as the media affecting the magnetic relaxation properties of gadolinium ions trapped by metal-oxide nanostructures
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.111821
Abstract: Abstract The present work introduces the optimization of the oxidative degradation, complex formation and aggregation of the water-soluble metal oxide nanostructures (the so-called keplerates) [{W6O21(H2O)5(OAc)0.5}12{Mo2O4(OAc)}30]48− (W72Mo60), [{Mo6O21(H2O)3(SO4)}12(VO)30(H2O)20]26− (Mo72V30), and [{Mo6O21}12Fe30(OAc)12{Mo2O7(H2O)}2{H2Mo2O8(H2O)}(H2O)91] (Mo72Fe30) in aqueous solutions containing… read more here.
Keywords: oxide nanostructures; aqueous solutions; metal oxide; h2o ... See more keywords
Binding modes of Fe(III) with graphene oxide in aqueous solutions. Competition with Sr2+, Cs+, Na+ ions and Fe(III) chelators
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.112461
Abstract: Abstract The work is devoted to the analysis of the state of the Fe(III) ions in aqueous solutions of graphene oxide (GO) using NMR-relaxation method. The presence of graphene oxide in solution suppresses the hydrolysis… read more here.
Keywords: graphene oxide; iii graphene; modes iii; binding modes ... See more keywords
NMR characterizing mixed wettability under intermediate-wet condition.
Sign Up to like & getrecommendations! Published in 2019 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2018.09.023
Abstract: Applying the concept of effective relaxivity to characterize wettability is based on the configuration of fluid distributions in porous media. However, in mixed-wet porous media with intermediate-wet patches (homogeneous wetting region), effective surface relaxivity cannot… read more here.
Keywords: mixed wettability; surface relaxivity; intermediate wet; wettability ... See more keywords
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate Chemistry"
DOI: 10.1021/acs.bioconjchem.2c00506
Abstract: Biologics are emerging as the most important class of drugs and are used to treat a large variety of pathologies. Most of biologics are proteins administered in large amounts, either by intramuscular injection or by… read more here.
Keywords: gadolinium; contrast; labeled asparaginase; relaxivity ... See more keywords
High Relaxivity with No Coordinated Waters: A Seemingly Paradoxical Behavior of [Gd(DOTP)]5- Embedded in Nanogels.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c00225
Abstract: Nanogels (NGs) obtained by electrostatic interactions between chitosan and hyaluronic acid and comprising paramagnetic Gd chelates are gaining increasing attention for their potential application in magnetic resonance bioimaging. Herein, the macrocyclic complexes [Gd(DOTP)]5-, lacking metal-bound… read more here.
Keywords: relaxivity; relaxivity coordinated; high relaxivity; waters seemingly ... See more keywords
Enhancing r1 Relaxivity in GdDOTA-Monoamide Complexes through Polar Group-Mediated Ordering of Second-Sphere Water Molecules.
Sign Up to like & getrecommendations! Published in 2024 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.3c03639
Abstract: This study was designed to test whether the single appended phosphonate group in GdDOTA-1AmP is sufficient for catalyzing the exchange of proton from the single inner-sphere water-exchanging molecule. Unlike the other phosphonate derivatives in this… read more here.
Keywords: phosphonate; gddota 1amp; relaxivity; sphere water ... See more keywords
Mn(II), Cu(II), and Zn(II) Complexes Based on H3nota Derivatives Possessing Picolyl and Picolinate Pendants: Structural and Equilibrium Studies ─ Kinetic Inertness, Electrochemical Properties, and Relaxivity of the Mn Complexes.
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.5c02705
Abstract: Two derivatives of tacn (1,4,7-triazacyclononane) are investigated for their complexation with Cu(II), Zn(II), and Mn(II). The different denticities of macrocyclic ligands Hnoapy and H2noapa offer the possibility to modulate the coordination environment and stability of… read more here.
Keywords: h3nota derivatives; relaxivity; noapy clo4; geometry ... See more keywords
Structure-Relaxivity Mechanism of an Ultrasmall Ferrite Nanoparticle T1 MR Contrast Agent: The Impact of Dopants Controlled Crystalline Core and Surface Disordered Shell.
Sign Up to like & getrecommendations! Published in 2021 at "Nano letters"
DOI: 10.1021/acs.nanolett.0c04574
Abstract: Ultrasmall ferrite nanoparticles (UFNPs) have emerged as powerful magnetic resonance imaging (MRI) T1 nanoprobe for noninvasive visualization of biological events. However, the structure-relaxivity relationship and regulatory mechanism of UFNPs remain elusive. Herein, we developed chemically… read more here.
Keywords: structure relaxivity; crystalline core; ultrasmall ferrite; shell ... See more keywords