Autoimmune-Mediated Thymic Atrophy Is Accelerated but Reversible in RelB-Deficient Mice
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DOI: 10.3389/fimmu.2018.01092
Abstract: Polymorphisms impacting thymic function may decrease peripheral tolerance and hasten autoimmune disease. The NF-κB transcription factor subunit, RelB, is essential for the development and differentiation of medullary thymic epithelial cells (mTECs): RelB-deficient mice have reduced… read more here.
Keywords: relb deficient; autoimmune mediated; mice; deficient mice ... See more keywords