UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis
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DOI: 10.1002/advs.202412571
Abstract: Chronic pancreatitis (CP) is a progressive inflammatory disease characterized by pancreatic fibrosis and functional decline. Here, we identify macrophage‐to‐myofibroblast transition (MMT) as a novel feature of CP and investigate the role of mitochondrial uncoupling protein… read more here.
Keywords: macrophage; acinar cells; chronic pancreatitis; release acinar ... See more keywords