Gating and regulation of the calcium release‐activated calcium channel: Recent progress from experiments and molecular modeling
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DOI: 10.1002/bip.23392
Abstract: Calcium release‐activated calcium (CRAC) channels are highly calcium ion (Ca2+)‐selective channels in the plasma membrane. The transient drop of endoplasmic reticulum Ca2+ level activates its calcium sensor stromal interaction molecule (STIM) and then triggers the… read more here.
Keywords: calcium release; activated calcium; gating regulation; calcium ... See more keywords
Insights into the dynamics of the Ca2+ release-activated Ca2+ channel pore-forming complex Orai1.
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DOI: 10.1042/bst20230815
Abstract: An important calcium (Ca2+) entry pathway into the cell is the Ca2+ release-activated Ca2+ (CRAC) channel, which controls a series of downstream signaling events such as gene transcription, secretion and proliferation. It is composed of… read more here.
Keywords: orai1; ca2; release activated; ca2 release ... See more keywords