Articles with "release approach" as a keyword



Microwave-Dependent Thermo-Release Approach for Oligonucleotides 5'-Phosphorylation.

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Published in 2024 at "Organic letters"

DOI: 10.1021/acs.orglett.3c03924

Abstract: A method for phosphorylating oligonucleotides using a thermosensitive "trigger" is hereby presented. The recovery of the phosphate specifically takes place under neutral conditions when subjected to an elevated temperature. Two identical thermolabile protecting groups are… read more here.

Keywords: thermo release; release; approach oligonucleotides; release approach ... See more keywords