Dual-targeting Rutaecarpine-NO donor hybrids as novel anti-hypertensive agents by promoting release of CGRP.
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DOI: 10.1016/j.ejmech.2019.02.037
Abstract: CGRP, known as the most potent vasodilator substance, plays an important role in hypertension initiation and development. TRPV1 and TRPA1 are critical in promoting the synthesis and release of CGRP, thereby regulating the cardiovascular tone.… read more here.
Keywords: release cgrp; anti hypertensive; novel anti; rutaecarpine ... See more keywords