Extracellular release of damaged mitochondria induced by prehematopoietic stem cell transplant conditioning exacerbates GVHD
Sign Up to like & getrecommendations! Published in 2024 at "Blood Advances"
DOI: 10.1182/bloodadvances.2023012328
Abstract: Key Points • Pretransplant conditioning regimens induces release of damaged extracellular mitochondria independent of cell death.• Presence of circulating extracellular mitochondria activates host antigen-presenting cells and aggravates graft-versus-host disease. read more here.
Keywords: release damaged; damaged mitochondria; conditioning; cell ... See more keywords