Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules
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DOI: 10.18632/oncotarget.24158
Abstract: Disturbances in endoplasmic reticulum (ER) function lead to ER stress which, when severe or prolonged, may result in apoptosis. Severe ER stress has been implicated in several pathological conditions including pre-eclampsia, a multisystem disorder of… read more here.
Keywords: extracellular vesicles; severe stress; associated molecular; endoplasmic reticulum ... See more keywords
Macrophages Release Extracellular Vesicles of Different Properties and Composition Following Exposure to Nanoparticles
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DOI: 10.3390/ijms24010260
Abstract: Extracellular vesicles are membrane-bound carriers with complex cargoes, which play a major role in intercellular communication, for instance, in the context of the immune response. Macrophages are known to release extracellular vesicles in response to… read more here.
Keywords: extracellular vesicles; composition; macrophages release; exposure ... See more keywords
Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification
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DOI: 10.3390/ijms24032027
Abstract: Vascular calcification (VC) is an important contributor and prognostic factor in the pathogenesis of cardiovascular diseases. VC is an active process mediated by the release of extracellular vesicles by vascular smooth muscle cells (VSMCs), and… read more here.
Keywords: calcification; extracellular vesicles; vascular smooth; vesicles vascular ... See more keywords