A population pharmacokinetic model taking into account protein binding for the sustained-release granule formulation of valproic acid in children with epilepsy
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DOI: 10.1007/s00228-018-2444-2
Abstract: PurposeThe objective of this work was to develop a population pharmacokinetic model for a prolonged-release granule formulation of valproic acid (VPA) in children with epilepsy and to determine the doses providing a VPA trough concentration… read more here.
Keywords: release granule; pharmacokinetic model; granule formulation; formulation valproic ... See more keywords