Controlled Release of Hydrophilic Drug from Hollow Nanodots.
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DOI: 10.1002/smll.202409112
Abstract: Here the challenge of limited encapsulation efficiency of ionizable hydrophilic molecules in silica materials is addressed. Two effective strategies are showcased that allow high encapsulation efficiency of salicylic acid, while simultaneously maintaining the morphology and… read more here.
Keywords: encapsulation efficiency; silica nanocapsules; hydrophilic drug; release hydrophilic ... See more keywords
Tailoring the properties of mPEG-PLLA nanoparticles for better encapsulation and tuned release of the hydrophilic anticancer drug
Sign Up to like & getrecommendations! Published in 2017 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-017-0372-9
Abstract: Gemcitabine is used as a first-line drug for treating many solid tumours. However, it suffers from a major drawback of strong side effects and short plasma half-life because of degradation by enzyme when administered intravenously.… read more here.
Keywords: release hydrophilic; mpeg plla; tuned release; drug ... See more keywords
Silica Nanobottles Filled with Photo-cross-linked GelMA for the Sustained Release of Hydrophilic Biomacromolecules.
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DOI: 10.1021/acs.nanolett.5c04288
Abstract: Nanobottles have garnered attention as a class of advanced carriers for drug delivery, because of their advantages, such as convenient loading, high capacity, and a well-defined wall for surface modification. However, strategies to achieve sustained… read more here.
Keywords: sustained release; release; silica nanobottles; photo cross ... See more keywords
Morphology-dependent pH-responsive release of hydrophilic payloads using biodegradable nanocarriers
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DOI: 10.1039/c8ra07066k
Abstract: The development of functional nanocarriers with stimuli-responsive properties has advanced tremendously to serve biomedical applications such as drug delivery and regenerative medicine. However, the development of biodegradable nanocarriers that can be loaded with hydrophilic compounds… read more here.
Keywords: release hydrophilic; dependent responsive; biodegradable nanocarriers; morphology dependent ... See more keywords