Articles with "release mini" as a keyword



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Development of Extended-Release Mini-Tablets Containing Metoprolol Supported by Design of Experiments and Physiologically Based Biopharmaceutics Modeling

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14050892

Abstract: The development of extended-release dosage forms with adequate drug release is a challenge for pharmaceutical companies, mainly when the drug presents high solubility, as in Biopharmaceutics Classification System (BCS) class I. This study aimed to… read more here.

Keywords: release mini; mini tablets; development; release ... See more keywords
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Novel Esomeprazole Magnesium-Loaded Dual-Release Mini-Tablet Polycap: Formulation, Optimization, Characterization, and In Vivo Evaluation in Beagle Dogs

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14071411

Abstract: Esomeprazole magnesium (EMP) is a proton pump inhibitor (PPI) that reduces acid secretion. EMP has a short plasma half-life (approximately 1.3 h); hence, nocturnal acid breakthrough (NAB) frequently occurs, disturbing the patient’s nighttime comfort and… read more here.

Keywords: mini tablet; polycap; release mini; release ... See more keywords