Development and optimization of guaifenesin sustained release mini-tablets for adult and geriatric patients.
Sign Up to like & getrecommendations! Published in 2024 at "Therapeutic delivery"
DOI: 10.1080/20415990.2024.2406216
Abstract: Aim: The main aim of this study was to formulate and optimize sustained release mini-tablets of guaifenesin.Materials & methods: Guaifenesin granules were successfully prepared using different blend ratios of carnauba wax to drug by melt… read more here.
Keywords: release mini; sustained release; release; drug ... See more keywords
Development of Extended-Release Mini-Tablets Containing Metoprolol Supported by Design of Experiments and Physiologically Based Biopharmaceutics Modeling
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DOI: 10.3390/pharmaceutics14050892
Abstract: The development of extended-release dosage forms with adequate drug release is a challenge for pharmaceutical companies, mainly when the drug presents high solubility, as in Biopharmaceutics Classification System (BCS) class I. This study aimed to… read more here.
Keywords: release mini; mini tablets; development; release ... See more keywords
Novel Esomeprazole Magnesium-Loaded Dual-Release Mini-Tablet Polycap: Formulation, Optimization, Characterization, and In Vivo Evaluation in Beagle Dogs
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DOI: 10.3390/pharmaceutics14071411
Abstract: Esomeprazole magnesium (EMP) is a proton pump inhibitor (PPI) that reduces acid secretion. EMP has a short plasma half-life (approximately 1.3 h); hence, nocturnal acid breakthrough (NAB) frequently occurs, disturbing the patient’s nighttime comfort and… read more here.
Keywords: mini tablet; polycap; release mini; release ... See more keywords