Articles with "releasing factor" as a keyword



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Effects of early trauma and corticotropin‐releasing factor receptor 1 gene polymorphism on adult visual spatial memory

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Published in 2019 at "Molecular Genetics & Genomic Medicine"

DOI: 10.1002/mgg3.974

Abstract: The study sought to determine the effects of earthquake on the working memory of adults who experienced earthquake either as infants or fetuses and also investigates whether earthquake exposure and corticotropin‐releasing factor receptor 1 (CRHR1)… read more here.

Keywords: factor receptor; releasing factor; corticotropin releasing; memory ... See more keywords
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Probing the Interactome of Corticotropin-Releasing Factor Receptor Heteromers Using Mass Spectrometry.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9121-1_15

Abstract: Mass spectrometry is a sensitive technique used in the field of proteomics that allows for simultaneous detection and characterization of several proteins in a sample. It is also a powerful methodology to elucidate protein-protein interactions… read more here.

Keywords: releasing factor; mass spectrometry; corticotropin releasing; mass ... See more keywords
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Spexin as an anxiety regulator in mouse hippocampus: Mechanisms for transcriptional regulation of spexin gene expression by corticotropin releasing factor.

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Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.02.023

Abstract: Spexin (SPX) acts as a neuropeptide with pleiotropic functions that can participate in anxiety regulation. Corticotropin releasing factor (CRF) is widely expressed in brain tissues and associated with depression and anxiety and addiction. With the… read more here.

Keywords: releasing factor; spexin; anxiety; corticotropin releasing ... See more keywords
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Antagonism of corticotropin‐releasing factor CRF1 receptors blocks the enhanced response to cocaine after social stress

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Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.01.052

Abstract: Abstract Numerous studies have shown that social defeat stress induces an increase in the rewarding effects of cocaine. In this study we have investigated the role played by the main hypothalamic stress hormone, corticotropin‐releasing factor… read more here.

Keywords: cocaine; stress; corticotropin releasing; releasing factor ... See more keywords
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The effects of enhancing endocannabinoid signaling and blocking corticotrophin releasing factor receptor in the amygdala and hippocampus on the consolidation of a stressful event

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Published in 2017 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2017.06.006

Abstract: Current clinical and pre-clinical data suggest that both cannabinoid agents and blockage of CRF through corticotrophin releasing factor receptor type 1 (CRFr1) may offer therapeutic benefits for post-traumatic stress disorder (PTSD). Here we aim to… read more here.

Keywords: releasing factor; hippocampus; stressful event; corticotrophin releasing ... See more keywords
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Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.

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Published in 2020 at "Molecular cell"

DOI: 10.1016/j.molcel.2020.01.013

Abstract: Corticotropin-releasing factor (CRF) and the three related peptides urocortins 1-3 (UCN1-UCN3) are endocrine hormones that control the stress responses by activating CRF1R and CRF2R, two members of class B G-protein-coupled receptors (GPCRs). Here, we present… read more here.

Keywords: protein; corticotropin releasing; releasing factor; activation ... See more keywords
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Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations

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Published in 2020 at "Neuron"

DOI: 10.1016/j.neuron.2020.01.033

Abstract: In response to stressors, individuals adopt different behavioral styles, which are essential for survival and form the basis of differential susceptibility to stress-related disorders. Corticotropin-releasing factor (CRF) and the medial prefrontal cortex (mPFC) have predominantly been… read more here.

Keywords: releasing factor; corticotropin releasing; stress; behavioral style ... See more keywords
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Corticotropin releasing factor, but not alcohol, modulates norepinephrine release in the rat central nucleus of the amygdala

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Published in 2020 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2020.108293

Abstract: Alcohol misuse and dependence is a widespread health problem. The central nucleus of the amygdala (CeA) plays important roles in both the anxiety associated with alcohol (ethanol) dependence and the increased alcohol intake that is… read more here.

Keywords: releasing factor; central nucleus; alcohol; nucleus amygdala ... See more keywords
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The brain oxytocin and corticotropin-releasing factor systems in grieving mothers: What we know and what we need to learn

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Published in 2021 at "Peptides"

DOI: 10.1016/j.peptides.2021.170593

Abstract: The bond between a mother and her child is the strongest bond in nature. Consequently, the loss of a child is one of the most stressful and traumatic life events that causes Prolonged Grief Disorder… read more here.

Keywords: releasing factor; child; corticotropin releasing; brain oxytocin ... See more keywords
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Immunization against gonadotropin-releasing factor (GnRF) in market gilts: Effect on growth and carcass parameters, and impact of immunization timing.

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Published in 2021 at "Research in veterinary science"

DOI: 10.1016/j.rvsc.2021.02.003

Abstract: Reproductive cycling in fattening gilts can be associated with undesirable effects, such as estrus-related aggressive behavior, reduced feed intake and, in production systems where gilts are co-housed with entire males, unwanted pregnancy. Immunization against Gonadotrophin… read more here.

Keywords: immunization; releasing factor; feed intake; growth ... See more keywords
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Central amygdala corticotropin-releasing factor neurons promote hyponeophagia but do not control alcohol drinking in mice

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Published in 2022 at "Molecular Psychiatry"

DOI: 10.1038/s41380-022-01496-9

Abstract: Corticotropin-releasing factor (CRF) signaling in the central nucleus of the amygdala (CeA) plays a critical role in rodent models of excessive alcohol drinking. However, the source of CRF acting in the CeA during alcohol withdrawal… read more here.

Keywords: drinking; cea; alcohol; crf ... See more keywords