Articles with "releasing hormone" as a keyword



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Incidence of Idiopathic Intracranial Hypertension in Individuals With Gonadotropin-Releasing Hormone Analogue Treatment for Gender Dysphoria in Sweden.

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Published in 2023 at "JAMA pediatrics"

DOI: 10.1001/jamapediatrics.2023.0656

Abstract: This cohort study examines the incidence of idiopathic intracranial hypertension (IHH) among individuals in Sweden undergoing gonadotropin-releasing hormone analogue (GnRHa) treatment for gender dysphoria. read more here.

Keywords: releasing hormone; gonadotropin releasing; idiopathic intracranial; hormone analogue ... See more keywords
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Reduced Numbers of Corticotropin‐Releasing Hormone Neurons in Narcolepsy Type 1

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Published in 2022 at "Annals of Neurology"

DOI: 10.1002/ana.26300

Abstract: Narcolepsy type 1 (NT1) is a chronic sleep disorder correlated with loss of hypocretin(orexin). In NT1 post‐mortem brains, we observed 88% reduction in corticotropin‐releasing hormone (CRH)‐positive neurons in the paraventricular nucleus (PVN) and significantly less… read more here.

Keywords: releasing hormone; hormone; corticotropin releasing; numbers corticotropin ... See more keywords
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Suppression of reactive oxygen species in endothelial cells by an antagonist of growth hormone‐releasing hormone

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Published in 2021 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.22879

Abstract: Growth hormone‐releasing hormone (GHRH) is a hypothalamic hormone, which regulates the secretion of growth hormone (GH) from the anterior pituitary gland. The effects of GHRH extend beyond the GH—insulin‐like growth factor I axis, and that… read more here.

Keywords: hormone; releasing hormone; hormone releasing; growth hormone ... See more keywords
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Role of gonadotropin-releasing hormone-II and its receptor in swine reproduction.

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Published in 2022 at "Molecular reproduction and development"

DOI: 10.1002/mrd.23662

Abstract: The pig represents the only livestock mammal capable of producing a functional protein for the second mammalian form of gonadotropin-releasing hormone (GnRH-II) and its receptor (GnRHR-II). To examine the role of GnRH-II and its receptor… read more here.

Keywords: releasing hormone; gonadotropin releasing; hormone; control ... See more keywords
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Exploring Dynamics and Noise in Gonadotropin-Releasing Hormone (GnRH) Signaling.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8618-7_19

Abstract: Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes. These are Gq-coupled receptors that mediate acute effects of GnRH on the exocytotic secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well… read more here.

Keywords: hormone; releasing hormone; gonadotropin releasing; gnrh signaling ... See more keywords
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Cancer-Specific Loss of Urocortin 3 in Human Renal Cancer

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Published in 2019 at "Advances in Therapy"

DOI: 10.1007/s12325-019-01141-y

Abstract: Introduction The corticotropin-releasing hormone (CRH) system, its receptors corticotropin-releasing hormone receptor 1 (CRHR1) and 2 (CRHR2), and its corresponding binding protein corticotropin-releasing hormone-binding protein (CRHBP) as well as the urocortin proteins—structural homologues to CRH, which… read more here.

Keywords: ucn3 mrna; releasing hormone; cancer specific; corticotropin releasing ... See more keywords
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Feasibility and efficacy of gonadotropin-releasing hormone agonists for the prevention of chemotherapy-induced ovarian insufficiency in patients with malignant ovarian germ cell tumours (KGOG 3048R).

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Published in 2020 at "European journal of cancer"

DOI: 10.1016/j.ejca.2020.03.030

Abstract: BACKGROUND This study assessed the effects of gonadotropin-releasing hormone agonists (GnRHa) on the prevention of chemotherapy-induced ovarian insufficiency among young patients with malignant ovarian germ cell tumour (MOGCT) receiving chemotherapy. METHODS This multicentre, retrospective study… read more here.

Keywords: chemotherapy; releasing hormone; menstrual resumption; gonadotropin releasing ... See more keywords
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Synthesis and biological evaluation of 3-(2-aminoethyl) uracil derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists.

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Published in 2018 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2017.12.095

Abstract: We investigated a series of uracil analogues by introducing various substituents on the phenyl ring of the N-3 aminoethyl side chain and evaluated their antagonistic activity against human gonadotropin-releasing hormone (GnRH) receptors. Analogues with substituents… read more here.

Keywords: releasing hormone; gonadotropin releasing; hormone gnrh; gnrh ... See more keywords
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Gonadotropin-releasing hormone receptor pathway affects the function of human EBV-transformed B lymphocytes in an age-independent way

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Published in 2021 at "Experimental Gerontology"

DOI: 10.1016/j.exger.2021.111471

Abstract: Immune system function changes during aging, but the molecular mechanisms of this phenomenon are not fully understood. The present study identified pathways that are associated with age-associated changes in human B lymphocytes. Initial in silico… read more here.

Keywords: age; hormone receptor; gonadotropin releasing; releasing hormone ... See more keywords
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Molecular cloning and characterization of a gonadotropin-releasing hormone receptor homolog in the Chinese mitten crab, Eriocheir sinensis.

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Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2018.05.006

Abstract: As an essential mediator in the Gonadotropin-releasing hormone (GnRH) signaling pathway, GnRH receptor (GnRHR) coupled to GnRH, plays an important role in activating the downstream pathway after stimulating a series of cascades to regulate reproduction.… read more here.

Keywords: releasing hormone; gonadotropin releasing; chinese mitten; crab eriocheir ... See more keywords
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Mathematical modeling of gonadotropin-releasing hormone signaling

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Published in 2017 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2016.08.022

Abstract: Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes to control reproduction. These are Gq-coupled receptors that mediate acute effects of GnRH on the exocytotic secretion of luteinizing hormone (LH) and follicle-stimulating hormone… read more here.

Keywords: hormone; releasing hormone; gonadotropin releasing; mathematical modeling ... See more keywords