Evaluation of testicular structure in mice after exposure to environmentally relevant doses of manganese during critical windows of development.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.111537
Abstract: Despite being an essential trace element with great importance for vital metabolic activities, the manganese (Mn) can also cause damage to organ systems. However, data on the effect of this metal on the male reproductive… read more here.
Keywords: structure mice; testicular structure; relevant doses; exposure ... See more keywords
Long-Term Exposure to Environmentally Relevant Doses of Large Polystyrene Microplastics Disturbs Lipid Homeostasis via Bowel Function Interference.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.1c07933
Abstract: The question of whether long-term chronic exposure to microplastics (MPs) could induce dose- and size-dependent adverse effects in mammals remains controversial and poorly understood. Our study explored potential health risks from dietary exposure to environmentally… read more here.
Keywords: long term; relevant doses; exposure environmentally; environmentally relevant ... See more keywords
Chronic Exposure to Environmentally Relevant Doses of Triphenyl Phosphate Induces Anxiety- and Depression-Like Behaviors in Mice via the Gut-Brain Axis.
Sign Up to like & getrecommendations! Published in 2025 at "Environmental science & technology"
DOI: 10.1021/acs.est.5c03124
Abstract: Triphenyl phosphate (TPHP) is an emerging endocrine-disrupting chemical that has been widely used as a flame retardant. Although the neurotoxicity of TPHP to aquatic animals had been highlighted in previous studies, its effects on mammals,… read more here.
Keywords: relevant doses; triphenyl phosphate; gut; environmentally relevant ... See more keywords
Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-019-0442-4
Abstract: Vortioxetine is a multimodal antidepressant approved for treatment of major depressive disorder. Preclinical studies have demonstrated that the mechanism of action of vortioxetine might be different from selective serotonin reuptake inhibitors (SSRIs), including larger serotonin… read more here.
Keywords: vortioxetine; pet; relevant doses; effect ... See more keywords
Clinically relevant doses of tiludronate do not affect bone remodelling in pasture‐exercised horses
Sign Up to like & getrecommendations! Published in 2024 at "Equine Veterinary Journal"
DOI: 10.1111/evj.14119
Abstract: Abstract Background Bisphosphonates are widely used in equine athletes to reduce lameness associated with skeletal disorders. Widespread off‐label use has led to concern regarding potential negative effects on bone healing, but little evidence exists to… read more here.
Keywords: clinically relevant; relevant doses; bone remodelling; tuber coxae ... See more keywords