Clinically relevant fusion oncogenes: detection and practical implications
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221144108
Abstract: Mechanistically, chimeric genes result from DNA rearrangements and include parts of preexisting normal genes combined at the genomic junction site. Some rearranged genes encode pathological proteins with altered molecular functions. Those which can aberrantly promote… read more here.
Keywords: fusion; fusion oncogenes; rtk fusion; relevant fusion ... See more keywords