Abstract 5232: The molecular basis for specific recognition of the biologically relevant hybrid-2 type human telomeric G-quadruplex by epiberberine
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DOI: 10.1158/1538-7445.am2017-5232
Abstract: G-quadruplex structures have been shown to form in human telomeres, and the formation of G-quadruplexes can inhibit telomerase, which plays a key role in cancers by stabilizing telomere length and integrity thereby granting limitless replicative… read more here.
Keywords: human telomeric; telomeric quadruplex; hybrid type; specific recognition ... See more keywords