What Features of Ligands Are Relevant to the Opening of Cryptic Pockets in Drug Targets?
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DOI: 10.3390/informatics9010008
Abstract: Small-molecule drug design aims to identify inhibitors that can specifically bind to a functionally important region on the target, i.e., an active site of an enzyme. Identification of potential binding pockets is typically based on… read more here.
Keywords: cryptic pockets; relevant opening; opening cryptic; features ligands ... See more keywords