Two single-nucleotide polymorphisms of the RELN gene and symptom-based and developmental deficits among children and adolescents with autistic spectrum disorders in the Tianjin, China
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.04.048
Abstract: ABSTRACT Increasing evidence has revealed that genetic variants in Reelin (RELN) gene, especially single‐nucleotide polymorphisms (SNPs), correlate with autistic spectrum disorders (ASD) risk; however, no consensus have been reached. This study aimed to provide additional… read more here.
Keywords: reln gene; single nucleotide; based developmental; symptom based ... See more keywords
Heterozygous missense mutation of the RELN gene is one of the causes of epilepsy.
Sign Up to like & getrecommendations! Published in 2021 at "Neurological research"
DOI: 10.1080/01616412.2021.1979748
Abstract: OBJECTIVES Genetic factors play an important role in the onset of epilepsy, and the involvement of the RELN gene was recently discovered. This paper reports a family with a history of epilepsy caused by a… read more here.
Keywords: reln gene; heterozygous missense; mutation reln; missense mutation ... See more keywords