Impaired glycinergic transmission in hyperekplexia: a model of parasomnia overlap disorder
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50866
Abstract: We report sleep phenotypes and polysomnographic findings in two siblings with a novel homozygous variant of the GLRA1 gene causing hereditary hyperekplexia (HH). Both sisters had startles during wakefulness and sleep, sleep terrors, and one… read more here.
Keywords: impaired glycinergic; rem sleep; glycinergic transmission; disorder ... See more keywords
Rhythm disturbances as a potential early marker of Parkinson’s disease in idiopathic REM sleep behavior disorder
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50982
Abstract: We aimed to identify timing distortions in production and perception of rhythmic events in patients with idiopathic REM sleep behavior disorder (iRBD) as early markers of Parkinson's disease (PD). read more here.
Keywords: behavior disorder; idiopathic rem; rem sleep; sleep behavior ... See more keywords
Nicotine‐prevented learning and memory impairment in REM sleep‐deprived rat is modulated by DREAM protein in the hippocampus
Sign Up to like & getrecommendations! Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.704
Abstract: REM sleep deprivation is associated with impairment in learning and memory, and nicotine treatment has been shown to attenuate this effect. Recent studies have demonstrated the importance of DREAM protein in learning and memory processes.… read more here.
Keywords: dream protein; rem sleep; learning memory;
Do all mammals dream?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24860
Abstract: The presence of dreams in human sleep, especially in REM sleep, and the detection of physiologically similar states in mammals has led many to ponder whether animals experience similar sleep mentation. Recent advances in our… read more here.
Keywords: dream; mentation; rem sleep; non rem ... See more keywords
Rapid eye movement sleep patterns of brain activation and deactivation occur within unique functional networks
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25102
Abstract: Abstract Rapid eye movement (REM) sleep is a paradoxical state where the individual appears asleep while the electroencephalogram pattern resembles that of wakefulness. Regional differences in brain metabolism have been observed during REM sleep compared… read more here.
Keywords: activation deactivation; rem sleep; rapid eye; activation ... See more keywords
Deep Learning‐Based Neuromelanin MRI Changes of Isolated REM Sleep Behavior Disorder
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.28933
Abstract: Isolated REM sleep behavior disorder (iRBD) is considered a prodromal stage of parkinsonism. Neurodegenerative changes in the substantia nigra pars compacta (SNc) in parkinsonism can be detected using neuromelanin‐sensitive MRI. read more here.
Keywords: isolated rem; sleep behavior; rem sleep; behavior disorder ... See more keywords
Neural Circuits for Sleep-Wake Regulation.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-7086-5_8
Abstract: The neural mechanisms of sleep, a fundamental biological behavior from invertebrates to humans, have been a long-standing mystery and present an enormous challenge. Gradually, perspectives on the neurobiology of sleep have been more various with… read more here.
Keywords: sleep wake; circuits sleep; rem sleep; cholinergic system ... See more keywords
Association between REM sleep behavior disorder and impulsive–compulsive behaviors in Parkinson’s disease: a systematic review and meta-analysis of observational studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09588-3
Abstract: Background Both REM sleep behavior disorder (RBD) and impulsive–compulsive behaviors (ICBs) are well-recognized non-motor features in patients with Parkinson’s disease (PD). Studies have given contradictory results about the potential association between RBD and ICBs. Methods… read more here.
Keywords: behavior disorder; compulsive behaviors; rem sleep; rbd ... See more keywords
Clinical profiles of late-onset psychiatric patients exhibiting incidental REM sleep without atonia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-019-02035-7
Abstract: Rapid eye movement (REM) sleep without atonia (RWA), which is a hallmark of REM sleep behavior disorder (RBD) on polysomnography (PSG), may represent specific characteristics of prodromal Parkinson’s disease (PD)/dementia with Lewy bodies (DLB), even… read more here.
Keywords: late onset; incidental rwa; rwa; rem sleep ... See more keywords
Muscarinic Acetylcholine Receptors Chrm1 and Chrm3 Are Essential for REM Sleep.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.07.082
Abstract: Sleep regulation involves interdependent signaling among specialized neurons in distributed brain regions. Although acetylcholine promotes wakefulness and rapid eye movement (REM) sleep, it is unclear whether the cholinergic pathway is essential (i.e., absolutely required) for… read more here.
Keywords: rem sleep; chrm1 chrm3; sleep; acetylcholine receptors ... See more keywords
A patient with childhood-onset aggressive parasomnia diagnosed 50 years later with idiopathic REM sleep behavior disorder and a history of sleepwalking
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2017.07.001
Abstract: Rapid eye movement (REM) sleep behavior disorder (RBD) is defined as a parasomnia involving disruptive and violent dream-enacting behaviors associated with the loss of normal muscle atonia during REM sleep. RBD has been described predominantly… read more here.
Keywords: behavior disorder; rem sleep; aggressive parasomnia; sleep behavior ... See more keywords