Some remaining challenges regarding multiple endpoints in clinical trials.
Sign Up to like & getrecommendations! Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.7390
Abstract: Despite recent advance in methods for handling multiple endpoints in clinical trials, some challenges remain. This paper discusses some of these challenges, including confusion surrounding the terminology used to describe the multiple endpoints, the justification… read more here.
Keywords: regarding multiple; endpoints clinical; challenges regarding; clinical trials ... See more keywords
High-throughput organ-on-a-chip systems: Current status and remaining challenges
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Biomedical Engineering"
DOI: 10.1016/j.cobme.2018.02.004
Abstract: Abstract Organ-on-a-chip (OoC) systems might be the disruptive technology pharmaceutical industry has been looking for to tackle their ever-increasing R&D costs. First endeavors are well underway to transfer this technology, which was until now used… read more here.
Keywords: status; throughput; organ chip; remaining challenges ... See more keywords
Where are we with injectables against HIV infection and what are the remaining challenges?
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2018.1430570
Abstract: ABSTRACT Introduction: Drug adherence has been a recurring issue in the field of HIV treatment, and low treatment adherence is typically associated with emergence of drug resistance, treatment failure and increased risks of transmission. Injectable… read more here.
Keywords: hiv infection; treatment; drug; remaining challenges ... See more keywords
Recent Advances and Remaining Challenges in Manufacturing of Amorphous and Nanocrystalline Alloys
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Magnetics"
DOI: 10.1109/tmag.2022.3163713
Abstract: A review of advanced Fe-based amorphous and nanocrystalline soft magnetic alloys that are currently being used in the market and their primary industrial applications is discussed as well as emerging trends. The high-efficiency distribution transformer… read more here.
Keywords: advances remaining; remaining challenges; amorphous nanocrystalline; nanocrystalline alloys ... See more keywords
RNA interactomics: recent advances and remaining challenges
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DOI: 10.12688/f1000research.16146.1
Abstract: Tight regulation of cellular processes is key to the development of complex organisms but also vital for simpler ones. During evolution, different regulatory systems have emerged, among them RNA-based regulation that is carried out mainly… read more here.
Keywords: interactomics recent; rna; rna interactomics; remaining challenges ... See more keywords
Lead Data Mapping to Prioritize US Locations for Whole-of-Government Exposure Prevention Efforts: State of the Science, Federal Collaborations, and Remaining Challenges.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of public health"
DOI: 10.2105/ajph.2022.307051
Abstract: For this state-of-science overview of geospatial approaches for identifying US communities with high lead-exposure risk, we compiled and summarized public data and national maps of lead indices and models, environmental lead indicators, and children's blood… read more here.
Keywords: remaining challenges; whole government; lead data; state science ... See more keywords
Cardiac Troponin Biosensor Designs: Current Developments and Remaining Challenges
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147728
Abstract: Acute myocardial infarction (AMI) is considered as one of the main causes of death, threating human lives for decades. Currently, its diagnosis relies on electrocardiography (ECG), which has been proven to be insufficient. In this… read more here.
Keywords: remaining challenges; biosensor designs; troponin biosensor; troponin ... See more keywords