Comparison of Time to Clinical Improvement With vs Without Remdesivir Treatment in Hospitalized Patients With COVID-19
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DOI: 10.1001/jamanetworkopen.2021.3071
Abstract: Key Points Question Does time to clinical improvement or time to death differ among hospitalized patients treated with vs without remdesivir (alone or with corticosteroids) for coronavirus disease 2019 outside of a clinical trial? Findings… read more here.
Keywords: remdesivir; clinical improvement; hospitalized patients; time clinical ... See more keywords
Remdesivir in Patients With Severe Kidney Dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.29236
Abstract: This secondary analysis of a randomized clinical trial examines the risk of kidney or hepatic toxic effects among patients with impaired kidney function at baseline treated with remdesivir. read more here.
Keywords: severe kidney; kidney; kidney dysfunction; patients severe ... See more keywords
COVID‐19 Patients Benefitting From Remdesivir for Improved Survival: A Neural Network‐Based Approach
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DOI: 10.1002/jmv.70276
Abstract: Conflicting results from randomized trials regarding the efficacy of remdesivir for COVID‐19 have been reported. We aimed to develop a neural network (NN) to identify COVID‐19 patients who would derive the greatest survival benefit from… read more here.
Keywords: covid patients; covid; mortality; remdesivir ... See more keywords
Flow Injection Analysis With UV Detection Versus Raman Spectroscopy for the Quantitative Analysis of Remdesivir
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DOI: 10.1002/jrs.6723
Abstract: The quality and the security of preparations in hospital centres are essential to guarantee the patient's safety. The development of fast and efficient analytical methods is required to control the finished product before use. In… read more here.
Keywords: spectroscopy; raman spectroscopy; injection analysis; remdesivir ... See more keywords
Efficacy and safety of remdesivir in hospitalized Covid‐19 patients: Systematic review and meta‐analysis including network meta‐analysis
Sign Up to like & getrecommendations! Published in 2020 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2187
Abstract: Remdesivir is an antiviral agent that has shown broad‐spectrum activity, including against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Clinical trials investigating the role of remdesivir in coronavirus disease 2019 (Covid‐19) reported conflicting results. This… read more here.
Keywords: covid patients; remdesivir; rate; meta analysis ... See more keywords
Remdesivir bei Patienten mit schwerer COVID-19
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DOI: 10.1007/s00108-020-00800-5
Abstract: Seit der ersten beschriebenen Infektion mit dem „severe acute respiratory syndrome coronavirus 2“ (SARS-CoV-2) im Dezember 2019 hat sich die „coronavirus disease 2019“ (COVID-19) zu einer Pandemie entwickelt, deren Symptomatik vom asymptomatischen Verlauf bis hin… read more here.
Keywords: bei patienten; patienten mit; remdesivir; mit ... See more keywords
Remdesivir for the Treatment of COVID-19: A Narrative Review
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DOI: 10.1007/s40121-023-00900-3
Abstract: When people get sick with COVID-19, which is caused by the SARS-CoV-2 virus, treatment with an antiviral may be needed to prevent serious illness. Remdesivir is an antiviral and was the first US Food and… read more here.
Keywords: treatment; time; remdesivir; narrative review ... See more keywords
Utility of SARS-CoV-2 Subgenomic RNA in Kidney Transplant Recipients Receiving Remdesivir
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DOI: 10.1007/s40121-024-00991-6
Abstract: There is no reliable microbiological marker to guide responses to antiviral treatment in kidney transplant recipients (KTR) with COVID-19. We aimed to evaluate the dynamics of subgenomic RNA (sgRNA) RT-PCR before and after receiving treatment… read more here.
Keywords: sars cov; treatment; transplant recipients; rna ... See more keywords
Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro
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DOI: 10.1016/j.antiviral.2020.104786
Abstract: An escalating pandemic by the novel SARS-CoV-2 virus is impacting global health and effective therapeutic options are urgently needed. We evaluated the in vitro antiviral effect of compounds that were previously reported to inhibit coronavirus… read more here.
Keywords: inhibit; remdesivir lopinavir; lopinavir emetine; remdesivir ... See more keywords
Remdesivir: Quo vadis?
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DOI: 10.1016/j.bcp.2021.114800
Abstract: Remdesivir (GS-5734, Veklury®) has remained the only antiviral drug formally approved by the US FDA for the treatment of Covid-19 (SARS-CoV-2 infection). Its key structural features are the fact that it is a C-nucleoside (adenosine)… read more here.
Keywords: remdesivir; pharmacology; remdesivir quo; quo vadis ... See more keywords
Safety of Remdesivir in Patients With Acute Kidney Injury or CKD
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DOI: 10.1016/j.ekir.2020.10.005
Abstract: P atients with chronic kidney disease (CKD), especially those with end-stage renal disease (ESRD), are susceptible to the development of severe coronavirus disease 2019 (COVID-19), which is associated with high mortality. Apart from respiratory support… read more here.
Keywords: kidney injury; acute kidney; remdesivir; ckd ... See more keywords