Comparison of pregabalin with magnesium sulfate in the prevention of remifentanil‐induced hyperalgesia in patients undergoing rhinoplasty: A randomized clinical trial
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DOI: 10.1002/lio2.905
Abstract: Remifentanil is usually used for controlled hypotension during rhinoplasty under general anesthesia (G/A). One of the complications of the remifentanil is postoperative hyperalgesia. In this study, we compare the effectiveness of pregabalin with that of… read more here.
Keywords: remifentanil; prevention; induced hyperalgesia; remifentanil induced ... See more keywords
Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05489-w
Abstract: Rationale A variety of neural systems are involved in drug addiction, and some of these systems are shared across different addictive drugs. We have found several different types of drug treatments that successfully reduce nicotine… read more here.
Keywords: self administration; administration; amitifadine triple; remifentanil ... See more keywords
Effect of remifentanil during cardiopulmonary bypass on incidence of acute kidney injury after cardiac surgery
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DOI: 10.1007/s00540-017-2419-y
Abstract: BackgroundAcute kidney injury (AKI) after cardiopulmonary bypass (CPB) is a well-known postoperative complication. Remifentanil, which is a commonly used ultra-short-acting opioid, has antiinflammatory and sympatholytic effects with improvement of microcirculation.MethodsA retrospective study was conducted to… read more here.
Keywords: incidence; surgery; remifentanil; cardiopulmonary bypass ... See more keywords
ED50 of remifentanil for providing excellent intubating conditions when co-administered with a single standard dose of propofol without the use of muscle relaxants in children: dose-finding clinical trial
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2502-z
Abstract: PurposePrevious studies evidenced that orotracheal intubation without neuromuscular blockers is feasible in children and has some potential advantages. Remifentanil has favorable pharmacodynamic and pharmacokinetic properties as an opioid for orotracheal intubation, but its dose for… read more here.
Keywords: remifentanil; propofol; propofol without; intubation ... See more keywords
Analgesic effects of methadone and magnesium following posterior spinal fusion for idiopathic scoliosis in adolescents: a randomized controlled trial
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DOI: 10.1007/s00540-018-2541-5
Abstract: PurposeTo provide optimal conditions for neurophysiological monitoring and rapid awakening, remifentanil is commonly used during pediatric spinal surgery. However, remifentanil may induce hyperalgesia and increase postoperative opioid requirements. We evaluated the potential of methadone or… read more here.
Keywords: spinal fusion; remifentanil; posterior spinal; magnesium ... See more keywords
High-dose intraoperative remifentanil infusion increases early postoperative analgesic consumption: a prospective, randomized, double-blind controlled study
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DOI: 10.1007/s00540-018-2569-6
Abstract: PurposeThe purpose of this study was to determine whether intraoperative infusion of remifentanil induces acute tolerance to opioids, and compare the postoperative pain and opioid consumption by the effect site concentrations of remifentanil.MethodsOne hundred and… read more here.
Keywords: increases early; remifentanil; infusion; group group ... See more keywords
Combined Isoflurane-Remifentanil Anaesthesia Permits Resting-State fMRI in Children with Severe Epilepsy and Intellectual Disability
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DOI: 10.1007/s10548-020-00782-5
Abstract: Head motion is a significant barrier to functional MRI (fMRI) in patients who are unable to tolerate awake scanning, including young children or those with cognitive and behavioural impairments. General anaesthesia minimises motion and ensures… read more here.
Keywords: state; fmri children; remifentanil; intellectual disability ... See more keywords
A Role for Transmembrane Protein 16C/Slack Impairment in Excitatory Nociceptive Synaptic Plasticity in the Pathogenesis of Remifentanil-induced Hyperalgesia in Rats.
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DOI: 10.1007/s12264-021-00652-5
Abstract: Remifentanil is widely used to control intraoperative pain. However, its analgesic effect is limited by the generation of postoperative hyperalgesia. In this study, we investigated whether the impairment of transmembrane protein 16C (TMEM16C)/Slack is required… read more here.
Keywords: remifentanil; hyperalgesia; slack; remifentanil induced ... See more keywords
The opioid agonist remifentanil increases subjective pleasure.
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DOI: 10.1016/j.bja.2019.03.031
Abstract: EditordThe endogenous opioid system is involved in modulation of both pain and pleasure. The opioid system also contributes to mood regulation. In short-term use, exogenous opioids have been suggested to increase positive mood and reduce… read more here.
Keywords: pleasure; emotional responses; remifentanil; infusion ... See more keywords
Remifentanil self-administration in mice promotes sex-specific prefrontal cortex dysfunction underlying deficits in cognitive flexibility
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DOI: 10.1038/s41386-021-01028-z
Abstract: Opioid-based drugs are frequently used for pain management in both males and females despite the known risk of prefrontal cortex dysfunction and cognitive impairments. Although poorly understood, loss of cognitive control following chronic drug use… read more here.
Keywords: self administration; administration; remifentanil; cognitive flexibility ... See more keywords
A dubious distinction for females: rapid achievement of prefrontal cortical hypoactivity and cognitive deficit upon remifentanil self-administration
Sign Up to like & getrecommendations! Published in 2021 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-021-01053-y
Abstract: Humans have long ingested opioids. In 1797, an opium-induced dream inspired Samuel Taylor Coleridge’s famous poem “Kubla Khan”. 100 years later, Arthur Conan Doyle’s Sherlock Holmes and Dr. Watson meet unexpectedly in an opium den… read more here.
Keywords: hypoactivity; self administration; remifentanil; exposure ... See more keywords