Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers
Sign Up to like & getrecommendations! Published in 2020 at "Anesthesiology"
DOI: 10.1097/aln.0000000000003103
Abstract: Background: Remimazolam (CNS 7056) is a new ultra–short-acting benzodiazepine for intravenous sedation and anesthesia. Its pharmacokinetics and pharmacodynamics have been reported for bolus administration. This study aimed to investigate the pharmacokinetics and pharmacodynamics of remimazolam… read more here.
Keywords: male volunteers; min min; infusion; remimazolam ... See more keywords
Effective anesthetic management with remimazolam and ketamine without muscle relaxants for parotidectomy in a patient with myotonic dystrophy: A case report
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030415
Abstract: Rationale: Patients with myotonic dystrophy (DM) are highly sensitive to anesthetics, muscle relaxants, and opioids, necessitating appropriate anesthetic management. Recently, remimazolam, an ultra-short-acting benzodiazepine, has been approved for use as a general anesthetic in Japan,… read more here.
Keywords: muscle relaxants; muscle; anesthetic management; myotonic dystrophy ... See more keywords
Efficacy and Safety of Remimazolam Tosilate Combined with Propofol in Digestive Endoscopy: A Randomised Trial
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1155/2023/9955312
Abstract: Current Knowledge and Objective. Remimazolam tosilate is a novel intravenous sedative of benzodiazepines with no tissue accumulation, which offers a faster onset of action and recovery time than midazolam. The aim of this trial was… read more here.
Keywords: rmp groups; combined propofol; group; remimazolam ... See more keywords
Unexpected tachycardia and hypertension during anesthetic induction with remimazolam in cardiac surgery: a case report
Sign Up to like & getrecommendations! Published in 2021 at "JA Clinical Reports"
DOI: 10.1186/s40981-021-00462-8
Abstract: © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you… read more here.
Keywords: creative commons; unexpected tachycardia; case; remimazolam ... See more keywords
Three cases of difficulty in achieving definitive loss of consciousness with remimazolam
Sign Up to like & getrecommendations! Published in 2022 at "JA Clinical Reports"
DOI: 10.1186/s40981-021-00485-1
Abstract: Background Remimazolam is a novel, ultra-short-acting benzodiazepine used for general anesthesia. Because remimazolam is an emerging drug, the tolerance to remimazolam in benzodiazepine-taking patients has been unclear. Also, the efficacy of remimazolam in different races… read more here.
Keywords: three cases; definitive loss; cases difficulty; difficulty achieving ... See more keywords
Factors affecting prolonged time to extubation in patients given remimazolam
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268568
Abstract: Purpose To analyze the cause of prolonged recovery from general anesthesia with remimazolam. Methods We studied 65 patients under general anesthesia with remimazolam. According to time to extubation, patients were divided into short period (SP)… read more here.
Keywords: time extubation; extubation; concentration; group ... See more keywords
Remimazolam: An Updated Review of a New Sedative and Anaesthetic
Sign Up to like & getrecommendations! Published in 2022 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s384155
Abstract: Abstract Remimazolam (CNS7056) is a novel benzodiazepine for intravenous sedation; it has an ultra-short duration of action and was recently approved for use in procedural sedation and general anaesthesia. It acts on γ-aminobutyric acid type… read more here.
Keywords: review new; updated review; remimazolam updated; new sedative ... See more keywords
Efficacy and Safety Profile of Remimazolam for Sedation in Adults Undergoing Short Surgical Procedures
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s304556
Abstract: Abstract Sedation for short-term procedures is increasingly being used in clinical practice. Selection of appropriate drugs is important for effective and safe sedation; however, an ideal sedative remains unavailable. Remimazolam is a novel, ultrafast-acting benzodiazepine… read more here.
Keywords: short surgical; surgical procedures; sedation; remimazolam ... See more keywords
Efficacy and Safety of Remimazolam in Endoscopic Sedation—A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.655042
Abstract: Background: The aim of this systematic review and meta-analysis was to investigate the efficacy and safety of remimazolam in clinical endoscopic procedure sedation. Methods: The authors searched the databases of PubMed, Embase, and Cochrane Library… read more here.
Keywords: review; meta analysis; sedation; remimazolam ... See more keywords
The hemodynamic stability of remimazolam compared with propofol in patients undergoing endoscopic submucosal dissection: A randomized trial
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.938940
Abstract: Objective Hypotension is common in propofol anesthesia. Whether remimazolam could reduce intraoperative hypotension remains unknown. We therefore tested the primary hypothesis that remimazolam reduces the incidence of intraoperative hypotension compared with propofol in adult patients… read more here.
Keywords: hypotension; propofol group; compared propofol; patients undergoing ... See more keywords
Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.690875
Abstract: A program to identify novel intravenous sedatives with a short and predictable duration of action was initiated in the late 1990’s by Glaxo Wellcome. The program focussed on the identification of ester-based benzodiazepine derivatives that… read more here.
Keywords: program; remimazolam; pharmacology; clinical clinical ... See more keywords