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Published in 2020 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2020.2950
Abstract: Key Points Question Is treatment with a fingolimod dose of 0.5 mg or 0.25 mg superior to glatiramer acetate, 20 mg, in reducing relapse activity over 12 months in adult participants aged 18 to 65…
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Keywords:
relapsing remitting;
treatment;
fingolimod;
multiple sclerosis ... See more keywords
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1
Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2591
Abstract: Peak width of Skeletonized Mean Diffusivity (PSMD), as a novel marker of white matter (WM) microstructure damage, is associated with cognitive decline in several WM pathologies (i.e., small vessel disorders). We hypothesized that markers combining…
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Keywords:
relapsing remitting;
remitting multiple;
skeletonized mean;
mean diffusivity ... See more keywords
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Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.699
Abstract: Sexual dysfunction (SD) is one of the common symptoms of multiple sclerosis (MS) and is often underdiagnosed, especially in women. Relapsing‐remitting multiple sclerosis (RRMS) is the most widespread form of the disease, but the data…
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Keywords:
sclerosis;
female patients;
sexual dysfunction;
relapsing remitting ... See more keywords
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Published in 2021 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27806
Abstract: The mechanisms driving primary progressive and relapsing–remitting multiple sclerosis (PPMS/RRMS) phenotypes are unknown. Magnetic resonance imaging (MRI) studies support the involvement of gray matter (GM) in the degeneration, highlighting its damage as an early feature…
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Keywords:
progressive relapsing;
primary progressive;
relapsing remitting;
remitting multiple ... See more keywords
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Published in 2022 at "Journal of neuroscience research"
DOI: 10.1002/jnr.25035
Abstract: Herein, we combined neurite orientation dispersion and density imaging (NODDI) and synthetic magnetic resonance imaging (SyMRI) to evaluate the spatial distribution and extent of gray matter (GM) microstructural alterations in patients with relapsing-remitting multiple sclerosis…
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Keywords:
gray matter;
resonance imaging;
magnetic resonance;
relapsing remitting ... See more keywords
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Published in 2018 at "Der Nervenarzt"
DOI: 10.1007/s00115-018-0498-0
Abstract: BACKGROUND The selective modulation of lymphocyte numbers and function is an attractive concept in the treatment of relapsing-remitting multiple sclerosis (RMS). OBJECTIVE Cladribine tablets (Mavenclad®), an oral RMS medication with an innovative treatment concept, have…
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Keywords:
relapsing remitting;
treatment;
cladribine tablets;
disease activity ... See more keywords
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1
Published in 2018 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-018-3974-7
Abstract: PurposeExpression of the translocator protein (TSPO) is upregulated in activated macrophages/microglia and is considered to be a marker of neuroinflammation. We investigated the novel TSPO ligand [18F]GE-180 in patients with relapsing–remitting multiple sclerosis (RRMS) to…
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Keywords:
tspo;
pet;
relapsing remitting;
18f 180 ... See more keywords
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Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09288-y
Abstract: Alemtuzumab, a monoclonal antibody against CD52, is a highly effective treatment of relapsing–remitting multiple sclerosis (RRMS), but it is known to cause secondary autoimmunity in 40% of patients [1]. We present a case of a…
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Keywords:
relapsing remitting;
treatment;
treatment relapsing;
alemtuzumab ... See more keywords
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Published in 2022 at "Journal of Neurology"
DOI: 10.1007/s00415-022-11118-7
Abstract: To explore efficacy, risk factors, safety, and persistence of teriflunomide in relapsing–remitting multiple sclerosis (RRMS) cohort. This prospective, observational cohort study included 217 consecutive teriflunomide treated RRMS patients, 192 of which with at least 3-month…
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Keywords:
treatment;
remitting multiple;
multiple sclerosis;
teriflunomide relapsing ... See more keywords
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Published in 2020 at "Neurological Sciences"
DOI: 10.1007/s10072-020-04395-5
Abstract: Background The first years of relapsing-remitting multiple sclerosis (RRMS) constitute the most vulnerable phase for the progression of cognitive impairment (CImp), due to a gradual decrease of compensatory mechanisms. In the first 10 years of RRMS,…
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Keywords:
hippocampus;
volume;
relapsing remitting;
years relapsing ... See more keywords
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Published in 2020 at "Neurological Sciences"
DOI: 10.1007/s10072-020-04726-6
Abstract: Fingolimod, an oral sphingosine 1-phosphate receptor modulator, is approved by EMA for relapsing-remitting multiple sclerosis (RRMS). To assess the effectiveness and safety of fingolimod in patients with RRMS in real-world clinical practice in Portugal. Retrospective,…
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Keywords:
effectiveness safety;
relapsing remitting;
safety;
fingolimod ... See more keywords