Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.06.040
Abstract: Chromosomal rearrangements resulting in the fusion of TMPRSS2, an androgen-regulated gene, and the ETS family transcription factor ERG occur in over half of prostate cancers. However, the mechanism by which ERG promotes oncogenic gene expression… read more here.
Keywords: remodeling complexes; chromatin remodeling; baf; erg ... See more keywords
NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008463
Abstract: Nucleophosmin (NPM1) is frequently mutated or subjected to chromosomal translocation in acute myeloid leukemia (AML). NPM protein is primarily located in the nucleus, but the recurrent NPMc+ mutation, which creates a nuclear export signal, is… read more here.
Keywords: mlf1; remodeling complexes; npm mlf1; chromatin remodeling ... See more keywords
Roles of the INO80 and SWR1 Chromatin Remodeling Complexes in Plants
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DOI: 10.3390/ijms20184591
Abstract: Eukaryotic genes are packed into a dynamic but stable nucleoprotein structure called chromatin. Chromatin-remodeling and modifying complexes generate a dynamic chromatin environment that ensures appropriate DNA processing and metabolism in various processes such as gene… read more here.
Keywords: remodeling complexes; chromatin remodeling; chromatin; swr1 chromatin ... See more keywords
The Emerging Role of Chromatin Remodeling Complexes in Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213670
Abstract: Ovarian cancer (OC) is the fifth leading cause of women’s death from cancers. The high mortality rate is attributed to the late presence of the disease and the lack of modern diagnostic tools, including molecular… read more here.
Keywords: remodeling complexes; ovarian cancer; emerging role; chromatin remodeling ... See more keywords
Mutual Regulation of ncRNAs and Chromatin Remodeling Complexes in Normal and Pathological Conditions
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DOI: 10.3390/ijms24097848
Abstract: Chromatin remodeling is the one of the main epigenetic mechanisms of gene expression regulation both in normal cells and in pathological conditions. In recent years, a growing number of investigations have confirmed that epigenetic regulators… read more here.
Keywords: regulation ncrnas; pathological conditions; remodeling complexes; regulation ... See more keywords