Remodeling the conformational dynamics of I-motif DNA by helicases in ATP-independent mode at acidic environment
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DOI: 10.1016/j.isci.2021.103575
Abstract: Summary I-motifs are noncanonical four-stranded DNA structures formed by C-rich sequences at acidic environment with critical biofunctions. The particular pH sensitivity has inspired the development of i-motifs as pH sensors and DNA motors in nanotechnology.… read more here.
Keywords: dna; acidic environment; conformational dynamics; remodeling conformational ... See more keywords
Remodeling of the Conformational Dynamics of Noncanonical DNA Structures by Monomeric and Aggregated α-Synuclein.
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DOI: 10.1021/jacs.0c07192
Abstract: Research on Parkinson's disease most often focuses on the ability of the protein α-synuclein (α-syn) to form oligomers and amyloid fibrils, and how such species promote brain death. However, there are indications that α-syn also… read more here.
Keywords: monomeric aggregated; conformational dynamics; remodeling conformational; noncanonical dna ... See more keywords