Evaluation of genetic variants in nucleosome remodeling and deacetylase (NuRD) complex subunits encoding genes and gastric cancer susceptibility.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of toxicology"
DOI: 10.1007/s00204-022-03275-5
Abstract: Epigenetic complex NuRD (nucleosome remodeling and deacetylase) engages in a range of basic cellular processes, including chromatin modification. Changes in the activity of NuRD complex can influence gastric cancer progression. Multivariate logistic regression analyses were… read more here.
Keywords: cancer; expression; remodeling deacetylase; nucleosome remodeling ... See more keywords
The Methyl-CpG Binding Domain 2 and 3 proteins and formation of the Nucleosome Remodeling and Deacetylase complex.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.10.007
Abstract: The Nucleosome Remodeling and Deacetylase (NuRD) complex uniquely combines both deacetylase and remodeling enzymatic activities in a single macromolecular complex. The Methyl-CpG Binding Domain 2 and 3 (MBD2 and MBD3) proteins provide a critical structural… read more here.
Keywords: deacetylase; binding domain; remodeling deacetylase; methyl cpg ... See more keywords