DNA methylation and gene expression profiling reveal MFAP5 as a regulatory driver of extracellular matrix remodeling in varicose vein disease.
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DOI: 10.2217/epi-2018-0001
Abstract: AIM To integrate transcriptomic and DNA-methylomic measurements on varicose versus normal veins using a systems biological analysis to shed light on the interplay between genetic and epigenetic factors. MATERIALS & METHODS Differential expression and methylation… read more here.
Keywords: varicose vein; matrix remodeling; methylation; extracellular matrix ... See more keywords