MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening.
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DOI: 10.1038/s41418-021-00902-z
Abstract: Somatic cell reprogramming is an ideal model for studying epigenetic regulation as it undergoes dramatic chromatin remodeling. However, a role for phosphorylation signaling in chromatin protein modifications for reprogramming remains unclear. Here, we identified mitogen-activated… read more here.
Keywords: heterochromatin; heterochromatin loosening; map2k6 remodels; remodels chromatin ... See more keywords