Intramolecular Remote C-H Activation via Sequential 1,4-Palladium Migration To Access Fused Polycycles.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02392
Abstract: An unprecedented intramolecular remote C-H activation via sequential 1,4-palladium migration with an aromatic ring as a conveyor has been described. This reaction provides an efficient route to construct diverse polycyclic frameworks in moderate to good… read more here.
Keywords: palladium migration; intramolecular remote; remote activation;
Remote activation of nanoparticulate biomimetic activity by light triggered pH-jump.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc04279a
Abstract: Herein, we report a facile, efficient and versatile method for the photo-regulation of pH-dependent activities of artificial enzymes by incorporating flash photolysis reagents. Under light excitation, a persistent pH shift is achieved by proton release… read more here.
Keywords: nanoparticulate biomimetic; remote activation; activation; biomimetic activity ... See more keywords
Hydrolysis of Glycosyl Thioimidates by Glycoside Hydrolase Requires Remote Activation for Efficient Activity
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DOI: 10.3390/catal9100826
Abstract: Chemoenzymatic synthesis of glycosides relies on efficient glycosyl donor substrates able to react rapidly and efficiently, yet with increased stability towards chemical or enzymatic hydrolysis. In this context, glycosyl thioimidates have previously been used as… read more here.
Keywords: hydrolysis glycosyl; glycosyl thioimidates; glycosyl; remote activation ... See more keywords
Magnetic Ion Channel Activation (MICA)-Enabled Screening Assay: A Dynamic Platform for Remote Activation of Mechanosensitive Ion Channels
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043364
Abstract: This study reports results of a mechanical platform-based screening assay (MICA) to evaluate the remote activation of mechanosensitive ion channels. Here, we studied ERK pathway activation and the elevation in intracellular Ca2+ levels in response… read more here.
Keywords: screening assay; remote activation; mica; ion channels ... See more keywords