Articles with "remote homology" as a keyword



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A comprehensive review and comparison of different computational methods for protein remote homology detection

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Published in 2018 at "Briefings in Bioinformatics"

DOI: 10.1093/bib/bbw108

Abstract: Protein remote homology detection is one of the most fundamental and central problems for the studies of protein structures and functions, aiming to detect the distantly evolutionary relationships among proteins via computational methods. During the… read more here.

Keywords: computational methods; remote homology; protein remote; homology detection ... See more keywords
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Soft Ngram Representation and Modeling for Protein Remote Homology Detection

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Published in 2017 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"

DOI: 10.1109/tcbb.2016.2595575

Abstract: Remote homology detection represents a central problem in bioinformatics, where the challenge is to detect functionally related proteins when their sequence similarity is low. Recent solutions employ representations derived from the sequence profile, obtained by… read more here.

Keywords: remote homology; soft ngram; homology detection; profile ... See more keywords
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Protein remote homology detection based on bidirectional long short-term memory

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Published in 2017 at "BMC Bioinformatics"

DOI: 10.1186/s12859-017-1842-2

Abstract: BackgroundProtein remote homology detection plays a vital role in studies of protein structures and functions. Almost all of the traditional machine leaning methods require fixed length features to represent the protein sequences. However, it is… read more here.

Keywords: bidirectional long; remote homology; protein remote; homology detection ... See more keywords