Removal of empty capsids from high‐dose adeno‐associated virus 9 gene therapies
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DOI: 10.1002/bit.28737
Abstract: Recombinant adeno‐associated virus, serotype 9 (rAAV9) has shown promise as a gene therapy vector for muscle and central nervous diseases. High‐dose requirements of these therapies present critical safety considerations and biomanufacturing challenges. Notably, the reduction… read more here.
Keywords: adeno associated; empty capsids; removal empty; high dose ... See more keywords